Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429849 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL10774661 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL742283 | 0.86 | — | — | |
| Acetic Acid Butyl Ester SCHEMBL10748021 | 0.84 | ALDH1A1 (0.67) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL11458286 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL8593227 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL2547168 | 0.77 | PTGS2 (0.54) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL21105278 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| Acetic Acid Butyl Ester SCHEMBL28147997 | 0.77 | ALDH1A1 (0.75) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL189930 | 0.75 | ALDH1A1 (0.74) | ALDH1A1CHRM5CHRM1CHRM3PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-20090131483-A1 | 2-PYRIDINE DERIVATIVES AS INHIBITORS OF NEUTROPHILE ELASTASE | HANSEN PETER | 2009-05-21 | — | — | US | disclosed |
| EP-1861370-A1 | 2-PYRIDINE DERIVATIVES AS INHIBITORS OF NEUTROPHILE ELASTASE | AstraZeneca AB (SE) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006098683-A1 | 2-PYRIDINE DERIVATIVES AS INHIBITORS OF NEUTROPHILE ELASTASE | ASTRAZENECA AB (SE) | 2006-09-21 | — | — | WO | disclosed |
| EP-0529436-B1 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0464612-B1 | Silver halide photographic materials | FUJI PHOTO FILM CO LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| EP-0517214-B1 | Silver halide color photographic light-sensitive material, and method of processing the same | FUJI PHOTO FILM CO LTD (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5630927-A | DEVELOPMENT INHIBITOR RELEASING COUPLERS, COLOR FILMS, IMPROVED SHARPNESS, GRAININESS, STORAGE STABILITY, COLOR REPRODUCIBILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5547824-A | CONTAINING SILVER HALIDE GRAINS HAVING LOWER SILVER IODIDE CONTENT ON SURFACES, COMPOUND CAPABLE OF RELEASING PHOTOGRAPHICALLY USEFUL GROUP THROUGH TIMING GROUP | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5529894-A | PYRAZOLOAZOLE BASED MAGENTA COUPLER, TIMING COUPLER; SHARPNESS, DESILVERING PROPERTIES | FUJI PHOTO FILM CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| US-5422231-A | Exposure function | FUJI PHOTO FILM CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| US-5403703-A | Containing pyrazoloazole coupler and timing development inhibitor-releasing coupler; sharpness, color reproducibility, desilvering properties | FUJI PHOTO FILM CO., LTD. (JP) | 1995-04-04 | — | — | US | disclosed |
| US-5350666-A | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| US-5306603-A | Containing specified compound releasing photographically useful group and yellow-colored cyan coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0529436-A1 | Silver halide color photographic light-sensitive material, and method of processing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| EP-0523451-A1 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0517214-A1 | Silver halide color photographic light-sensitive material, and method of processing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| EP-0464612-A1 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4119646-A | Hexahydrobenzofuranone compounds | MOBIL OIL CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
| US-4011239-A | MANGANESE, VANADIUM, CERIUM | MOBIL OIL CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131483-A1 | 2-PYRIDINE DERIVATIVES AS INHIBITORS OF NEUTROPHILE ELASTASE | SERPINB1, ELANE, MPO | ALDH1A1 1548/4885CHRM5 837/4885CHRM1 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.