Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120840 | 0.87 | METTL3 (0.47) | MCHR1OPRD1METTL3KDM4ENPC1 | |
| SCHEMBL2121815 | 0.80 | HCRTR1 (0.54) | — | |
| SCHEMBL27808115 | 0.80 | KDM4E (0.54) | DAGLAABHD6KDM4EALDH1A1HPGD | |
| SCHEMBL4163082 | 0.80 | KDM4E (0.54) | DAGLAABHD6KDM4EALDH1A1HPGD | |
| SCHEMBL8160277 | 0.80 | HCRTR2 (0.38) | MCHR1METTL3DAGLAABHD6 | |
| SCHEMBL4176007 | 0.77 | KDM4E (0.39) | OPRD1DAGLAABHD6KDM4EALDH1A1 | |
| SCHEMBL3470831 | 0.77 | ALDH1A1 (0.39) | DAGLAABHD6KDM4ENPC1ALDH1A1 | |
| SCHEMBL2120937 | 0.73 | METTL3 (0.44) | OPRD1METTL3HRH3KDM4EALDH1A1 | |
| SCHEMBL4165845 | 0.73 | KDM4E (0.41) | DAGLAABHD6KDM4ENPC1ALDH1A1 | |
| SCHEMBL14893389 | 0.73 | OPRD1 (0.54) | OPRD1DAGLAABHD6HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090022670-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022670-A1 | NOVEL COMPOUNDS | UGT1A1, UGT2B7, ABCB1 | MCHR1 3773/4885OPRD1 8/4885METTL3 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.