SCHEMBL4154401

SCHEMBL4154401

O=C(c1ccccc1)c1ccc(OCCCCCCn2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.63
CNR2 P34972 1/20 0.60
PPARA Q07869 1/20 0.58
KDM4E B2RXH2 4/20 0.57
ALDH1A1 P00352 4/20 0.57
PLA2G2A P14555 2/20 0.55
GAA P10253 2/20 0.55
ACHE P22303 1/20 0.54
FABP4 P15090 2/20 0.54
FABP5 Q01469 2/20 0.54
LTA4H P09960 1/20 0.53
PSEN1 P49768 4/20 0.53
PSEN2 P49810 4/20 0.53
APH1B Q8WW43 4/20 0.53
NCSTN Q92542 4/20 0.53
APH1A Q96BI3 4/20 0.53
PSENEN Q9NZ42 4/20 0.53
MEN1 O00255 1/20 0.51
CYP2C9 P11712 1/20 0.51
HPGD P15428 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4154432 0.89 PLA2G2A (0.63) ALDH1A1PLA2G2AACHEFABP4FABP5
SCHEMBL16900464 0.87 PLA2G2A (0.50) HRH4CNR2PLA2G2AACHEFABP4
SCHEMBL16900271 0.85 ACHE (0.50) HRH4CNR2PPARAKDM4EALDH1A1
SCHEMBL4155967 0.83 MAPT (0.59) KDM4EALDH1A1PLA2G2AACHEFABP4
SCHEMBL2127003 0.83 PPARA (0.81) HRH4PPARAKDM4EALDH1A1GAA
SCHEMBL2127341 0.83 PPARA (0.81) HRH4PPARAKDM4EALDH1A1GAA
SCHEMBL20624042 0.83 PPARA (0.81) HRH4PPARAKDM4EALDH1A1GAA
SCHEMBL6652325 0.83 PPARA (0.81) HRH4PPARAKDM4EALDH1A1GAA
SCHEMBL14689477 0.83 PPARA (0.81) HRH4PPARAKDM4EALDH1A1GAA
SCHEMBL7114335 0.83 PPARA (0.81) HRH4PPARAKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079999-B2 Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings ADVINCULA RIGOBERTO (US) 2015-07-14 US disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed