Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559314 | 0.96 | MAPT (0.61) | MAPTRAB9AACHEMAPK1PSEN1 | |
| SCHEMBL350674 | 0.89 | PSEN1 (0.52) | ACHEMAPK1PSEN1PSEN2APH1B | |
| SCHEMBL4154432 | 0.85 | PLA2G2A (0.63) | ACHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4725248 | 0.85 | SCARB1 (0.52) | MAPTRAB9APSEN1PSEN2APH1B | |
| SCHEMBL4154401 | 0.83 | HRH4 (0.63) | ACHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4151119 | 0.83 | PSEN1 (0.47) | MAPTRAB9AACHEPSEN1PSEN2 | |
| SCHEMBL13011578 | 0.81 | TSHR (0.56) | MAPTRAB9AMAPK1PSEN1PSEN2 | |
| SCHEMBL2875809 | 0.81 | SCARB1 (0.49) | MAPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL24844734 | 0.80 | MAPT (0.90) | MAPTRAB9AL3MBTL1TDP1KDM4E | |
| SCHEMBL1003052 | 0.80 | HDAC6 (0.68) | RAB9ASCARB1HDAC1HDAC6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079999-B2 | Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings | ADVINCULA RIGOBERTO (US) | 2015-07-14 | — | — | US | disclosed |
| US-20090236229-A1 | METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-09-24 | — | — | US | disclosed |