SCHEMBL4154589

SCHEMBL4154589

Oc1csc(N2CCCC2)n1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 8/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ TP53 P04637 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ RAB9A P51151 4/20 0.47
▸ MEN1 O00255 2/20 0.42
▸ POLB P06746 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ NPC1 O15118 2/20 0.42
▸ PIK3CG P48736 1/20 0.40
▸ LMNA P02545 3/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.38
▸ ALDH1A1 P00352 2/20 0.37
▸ HPGD P15428 2/20 0.37
▸ DPP4 P27487 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4145551 0.82 LMNA (0.58) ARSMN1; SMN2RAB9AMEN1KMT2A
SCHEMBL18674626 0.77 AR (0.51) ARSMN1; SMN2TP53ALOX15HSD17B10
SCHEMBL3511935 0.75 L3MBTL1 (0.54) ARSMN1; SMN2TP53ALOX15HSD17B10
SCHEMBL18674673 0.75 AR (0.54) ARSMN1; SMN2TP53ALOX15HSD17B10
SCHEMBL22334869 0.75 AR (0.54) ARSMN1; SMN2TP53ALOX15HSD17B10
SCHEMBL18674672 0.75 AR (0.54) ARSMN1; SMN2TP53ALOX15HSD17B10
SCHEMBL17266285 0.75 AR (0.54) ARSMN1; SMN2TP53ALOX15HSD17B10
SCHEMBL2623930 0.75 RAB9A (0.56) ARSMN1; SMN2TP53ALOX15HSD17B10
SCHEMBL24362458 0.75 AR (0.46) ARSMN1; SMN2TP53ALOX15HSD17B10
SCHEMBL7185717 0.75 HRH3 (0.47) ARSMN1; SMN2TP53ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090074373-A1 OPTICAL FILTER KYOWA HAKKO CHEMICAL CO., LTD. (JP) 2009-03-19 — — US disclosed
EP-1813651-A1 OPTICAL FILTER Kyowa Hakko Chemical Co., Ltd. (JP) 2007-08-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074373-A1 OPTICAL FILTER SRSF7, C5, SF3B5 AR 1829/4885SMN1; SMN2 3267/4885TP53 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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