Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144446 | 0.84 | ADORA3 (0.48) | ALDH1A1MAPTSMN1; SMN2NPC1TP53 | |
| Hydrochloric Acid SCHEMBL4132360 | 0.81 | ADORA3 (0.46) | ALDH1A1MAPTSMN1; SMN2HDAC1HDAC3 | |
| SCHEMBL4132373 | 0.79 | ADORA3 (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1TP53 | |
| Hydrochloric Acid SCHEMBL4141950 | 0.77 | KDM4E (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1TP53 | |
| Hydrochloric Acid SCHEMBL4140741 | 0.76 | APP (0.53) | ALDH1A1MAPTSMN1; SMN2RAB9AHDAC1 | |
| SCHEMBL22573595 | 0.75 | MAPT (0.58) | ALDH1A1MAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL22573798 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL5264050 | 0.74 | ALDH1A1 (0.65) | ALDH1A1MAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL27664415 | 0.73 | MAPT (0.56) | ALDH1A1MAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL4560197 | 0.73 | ALDH1A1 (0.63) | ALDH1A1MAPTSMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | AJINOMOTO CO. INC (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-2009003-A1 | Production method of diaminopyrimidine compounds | Ajinomoto Co., Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | DPYD, DHPS, UMPS | ALDH1A1 165/4885MAPT 3920/4885SMN1; SMN2 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.