Sugi Predict

Sugi Predict / Compounds / SCHEMBL4155499

SCHEMBL4155499

SCHEMBL4155499

CNC(=O)c1cccc(C)c1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLK1 P53350 1/20 0.53
▸ GAA P10253 1/20 0.52
▸ NPC1 O15118 2/20 0.51
▸ RAB9A P51151 2/20 0.51
▸ TAS1R3 Q7RTX0 1/20 0.51
▸ TAS1R1 Q7RTX1 1/20 0.51
▸ TAS1R2 Q8TE23 1/20 0.51
▸ LMNA P02545 2/20 0.49
▸ HSD17B10 Q99714 2/20 0.49
▸ TP53 P04637 2/20 0.49
▸ TSHR P16473 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ MEN1 O00255 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ AKR1B10 O60218 1/20 0.47
▸ TRPA1 O75762 1/20 0.47
▸ ABCB11 O95342 1/20 0.47
▸ DHFR P00374 1/20 0.47
▸ MPO P05164 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30339452 1.00 PLK1 (0.53) PLK1GAANPC1RAB9ATAS1R3
SCHEMBL6671895 0.83 NPC1 (0.51) GAANPC1RAB9ATAS1R3TAS1R1
SCHEMBL29746319 0.83 HPGD (0.62) PLK1GAANPC1RAB9AHPGD
SCHEMBL311564 0.83 HPGD (0.62) PLK1GAANPC1RAB9AHPGD
SCHEMBL28681748 0.82 PLK1 (0.49) PLK1GAANPC1RAB9ATAS1R3
SCHEMBL14310585 0.82 ALDH1A1 (0.62) PLK1GAANPC1RAB9AHSD17B10
SCHEMBL14164188 0.82 PLK1 (0.52) PLK1GAANPC1RAB9ALMNA
SCHEMBL668153 0.82 P2RX7 (0.53) NPC1RAB9ATAS1R3TAS1R1TAS1R2
SCHEMBL6444002 0.82 NPC1 (0.50) GAANPC1RAB9ATAS1R3TAS1R1
SCHEMBL29274354 0.80 NPC1 (0.49) NPC1RAB9ATAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1547474-A Skin-permeable selective cyclooxygenase-2 inhibitor composition — 2004-11-17 — — CN claimed
CN-117355373-A Ethylene oligomerization process 切弗朗菲利浦化学公司 2024-01-05 — — CN disclosed
WO-2014067838-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-05-08 — — WO disclosed
CN-103764150-A Application of alcaftadine in treating urticaria ALLERGAN INC 2014-04-30 — — CN disclosed
CN-101918355-B Continuous method for producing amides of aromatic carboxylic acids CLARIANT INT LTD 2013-07-17 — — CN disclosed
CN-101983211-B Solid titanium catalyst component for ethylene polymerization, ethylene polymerization catalyst and ethylene polymerization method MITSUI CHEMICALS INC 2013-05-29 — — CN disclosed
CN-101842396-B Solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization method MITSUI CHEMICALS INC 2013-03-20 — — CN disclosed
US-20120016117-A1 INDAZOLEPROPIONIC ACID AMIDE COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-01-19 — — US disclosed
CN-101440179-B Polyolefin resin composition MITSUI CHEMICALS INC 2011-09-21 — — CN disclosed
US-7960567-B2 Compounds and methods useful for treating asthma and allergic inflammation AMGEN INC. (US) 2011-06-14 — — US disclosed
CN-1036344-C Solid titanium catalyst component for olefin polymerization, process for preparing the same, catalyst for olefin polymerization and process for olefin polymerization MITSUI PETROCHEMICAL IND (JP) 1997-11-05 — — CN disclosed
CN-1149879-A Process for preparing olefin polymer MITSUI PETROCHEMICAL IND (JP) 1997-05-14 — — CN disclosed
CN-1141304-A Solid titanium catalyst component, process for preparing same, olefin polymrization catalyst containing same, and olefin polymerization process MITSUI PETROCHEMICAL IND (JP) 1997-01-29 — — CN disclosed
CN-1140722-A Solid titanium catalyst component, ethylene polymerization catalyst containing the same, and ethylene polymerization process MITSUI PETROCHEMICAL IND (JP) 1997-01-22 — — CN disclosed
CN-1135491-A Vinyl unsaturated copolymer and preparation method thereof MATSUI PETRO CHEMICAL IND CO L (JP) 1996-11-13 — — CN disclosed
CN-1113494-A Prepolymerized catalyst, catalyst for olefin polymerization, polymerization process of olefin, and olefin polymer MITSUI PETROCHEMICAL IND (JP) 1995-12-20 — — CN disclosed
CN-1111658-A Polymer composition and core-shell elastomer for use in the composition MITSUI PETROCHEMICAL IND (JP) 1995-11-15 — — CN disclosed
CN-1087094-A Solid titanium catalyst component of olefinic polyreaction and preparation method thereof, the catalyzer of olefinic polyreaction and method thereof MITSUI PETROCHEMICAL IND (JP) 1994-05-25 — — CN disclosed
CN-1070651-A Catalyst for olefin polymerization and olefin polymer MITSUI PETROCHEMICAL IND (JP) 1993-04-07 — — CN disclosed
CN-1069279-A Olefin polymer compositions MITUSI PETROCHEMICAL INC LTD (JP) 1993-02-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016117-A1 INDAZOLEPROPIONIC ACID AMIDE COMPOUND SCN9A, SCN1A, SCN1B PLK1 4707/4885GAA 4762/4885NPC1 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.