Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671895 | 0.82 | NPC1 (0.51) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30339452 | 0.82 | PLK1 (0.53) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4155499 | 0.82 | PLK1 (0.53) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL668153 | 0.80 | P2RX7 (0.53) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29274354 | 0.78 | NPC1 (0.49) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL668073 | 0.78 | L3MBTL1 (0.51) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6901999 | 0.77 | MEN1 (0.51) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4155532 | 0.77 | KMT2A (0.50) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27928537 | 0.77 | NPC1 (0.48) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL25607328 | 0.77 | NPC1 (0.51) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562640-A2 | METHODS FOR PURIFYING RADIOLABELLED COMPOUNDS | Molecular Insight Pharmaceuticals, Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004035744-A2 | METHODS FOR PURIFYING RADIOLABELLED COMPOUNDS | BIOSTREAM, INC. (US) | 2004-04-29 | — | — | WO | disclosed |