Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 17/20 | 0.58 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996991 | 0.79 | KDM4E (0.60) | CLPPSLC6A5MEN1KMT2A | |
| SCHEMBL3435800 | 0.77 | CLPP (0.68) | CLPPMEN1KMT2A | |
| SCHEMBL14344451 | 0.76 | CLPP (0.67) | CLPP | |
| SCHEMBL5262540 | 0.75 | CLPP (0.65) | CLPPSLC6A5 | |
| SCHEMBL2849657 | 0.74 | CYP1A2 (0.66) | CLPP | |
| SCHEMBL20299228 | 0.72 | CLPP (0.62) | CLPP | |
| SCHEMBL2306231 | 0.72 | SLC6A5 (0.59) | CLPPSLC6A5KMT2A | |
| SCHEMBL17893717 | 0.72 | CLPP (0.61) | CLPP | |
| SCHEMBL12973482 | 0.72 | CLPP (0.61) | CLPPSLC6A5 | |
| SCHEMBL1550311 | 0.71 | KDM4E (0.63) | CLPPSLC6A5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137557-A1 | Calcilytic Compounds | CALCR, SOST, CALCB | CLPP 632/4885SLC6A5 1024/4885MEN1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.