Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162093 | 0.94 | NTRK1 (0.41) | SMOALDH1A1NTRK1DHODHTSHR | |
| SCHEMBL2138302 | 0.91 | P2RX7 (0.41) | DHODHMALT1DRD4 | |
| SCHEMBL4159757 | 0.91 | NTRK1 (0.38) | SMOALDH1A1NTRK1DHODHTSHR | |
| SCHEMBL499797 | 0.89 | NTRK1 (0.40) | SMOALDH1A1NTRK1TSHRMALT1 | |
| SCHEMBL121591 | 0.87 | DHODH (0.40) | DHODHMALT1 | |
| SCHEMBL4158292 | 0.86 | NTRK1 (0.42) | SMOALDH1A1NTRK1TSHRPOLB | |
| SCHEMBL2083746 | 0.86 | DHODH (0.42) | NTRK1DHODHMALT1POLBLMNA | |
| SCHEMBL31621733 | 0.86 | DHODH (0.42) | NTRK1DHODHMALT1 | |
| SCHEMBL950846 | 0.85 | DHODH (0.44) | ALDH1A1NTRK1DHODHMALT1MAPT | |
| SCHEMBL28425563 | 0.85 | DHODH (0.41) | NTRK1DHODHMALT1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812421-B9 | ANTHRANILAMIDE INSECTICIDES | DU PONT (US) | 2013-09-25 | — | — | EP | claimed |
| EP-1812421-B1 | ANTHRANILAMIDE INSECTICIDES | DU PONT (US) | 2013-04-24 | — | — | EP | claimed |
| US-20090133318-A1 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-28 | — | — | US | claimed |
| EP-1812421-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055922-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-26 | — | — | WO | claimed |
| EP-1812421-B9 | ANTHRANILAMIDE INSECTICIDES | DU PONT (US) | 2013-09-25 | — | — | EP | disclosed |
| EP-1812421-B1 | ANTHRANILAMIDE INSECTICIDES | DU PONT (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-2564706-A1 | Anthranilamide insecticides | E. I. du Pont de Nemours and Company (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20090133318-A1 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-28 | — | — | US | disclosed |
| EP-1812421-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055922-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090133318-A1 | Anthranilamide insecticides | C3AR1, C5, C1S | SMO 4094/4885ALDH1A1 937/4885NTRK1 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.