Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155986 | 0.89 | SMO (0.40) | NTRK1SMOALDH1A1TSHRMALT1 | |
| SCHEMBL951313 | 0.86 | KLKB1 (0.38) | ALDH1A1KLKB1MALT1MAPT | |
| SCHEMBL10253642 | 0.86 | CRACR2A (0.37) | KLKB1OPRL1 | |
| SCHEMBL12528985 | 0.86 | MALT1 (0.42) | KLKB1MALT1 | |
| SCHEMBL782368 | 0.85 | CARM1 (0.39) | ALDH1A1KLKB1MALT1MAPT | |
| SCHEMBL2293991 | 0.85 | P2RX7 (0.35) | NTRK1MALT1OPRL1 | |
| SCHEMBL1172990 | 0.85 | NTRK1 (0.39) | NTRK1KLKB1 | |
| SCHEMBL3679335 | 0.84 | PDE4B (0.37) | ALDH1A1KLKB1MALT1MAPT | |
| SCHEMBL17205424 | 0.84 | PDE4B (0.37) | NTRK1ALDH1A1KLKB1MALT1MAPT | |
| SCHEMBL13209133 | 0.84 | PDE4B (0.41) | ALDH1A1KLKB1MALT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106075-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-8106075-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-8106075-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20080275065-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080275065-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080275065-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275065-A1 | Novel Insecticides | DDT, ACHE, CYP4F11 | NTRK1 2247/4885SMO 4237/4885ALDH1A1 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.