Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901182 | 0.84 | MAOA (0.47) | LTA4HMAOBALDH1A1MAOACYP1A2 | |
| SCHEMBL7700570 | 0.82 | GSTP1 (0.44) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL21630308 | 0.81 | SOS1 (0.38) | — | |
| SCHEMBL21630390 | 0.81 | LTA4H (0.41) | LTA4HMAOBMITFALDH1A1MAOA | |
| SCHEMBL28575004 | 0.81 | S1PR2 (0.34) | LTA4HTSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL21630305 | 0.81 | TEAD4 (0.44) | ALDH1A1POLBHTTACHEMEN1 | |
| SCHEMBL21630310 | 0.81 | MAPT (0.44) | LTA4HTSHRMAOBALDH1A1MAOA | |
| SCHEMBL8126363 | 0.79 | LMNA (0.61) | LTA4HALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1451634 | 0.78 | LTA4H (0.50) | LTA4HTSHRMAOBAKR1C3MITF | |
| SCHEMBL7689247 | 0.77 | LTA4H (0.55) | LTA4HTSHRMAOBAKR1C3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118286-A1 | Heterobicyclic Acrylamides | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | US | claimed |
| CN-101171255-A | Heterobicyclic acrylamides | BAYER CROPSCIENCE AG (DE) | 2008-04-30 | — | — | CN | claimed |
| EP-1858899-A1 | HETEROBICYCLIC ACRYLAMIDES | Bayer CropScience AG (DE) | 2007-11-28 | — | — | EP | claimed |
| WO-2006094666-A1 | HETEROBICYCLIC ACRYLAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-09-14 | — | — | WO | claimed |
| EP-0833630-A4 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN INC (US) | 1998-09-02 | — | — | EP | claimed |
| EP-0833630-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | Sugen, Inc. (US) | 1998-04-08 | — | — | EP | claimed |
| WO-1996040110-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| CN-114920744-B | Non-covalent BTK kinase inhibitor and biological application thereof | 中国药科大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-117500806-A | Synthesis of BTK inhibitors and intermediates thereof | 默沙东有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-113307811-B | Tetrahydropyranyl amino-pyrrolopyrimidinones and methods of use thereof | 艾科尔公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-117042769-A | Substituted pyrrolopyrimidines and pyrazolopyrimidines as Bruton's Tyrosine Kinase (BTK) degrading agents | 冰洲石生物科技公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-114008042-B | Substituted pyrrolo [2,3-b ] pyridine and pyrazolo [3,4-b ] pyridine derivatives as protein kinase inhibitors | 重庆复尚源创医药技术有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-114761410-B | Pyrrolopyrimidinone compounds and application thereof | 广州必贝特医药股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2006094666-A1 | HETEROBICYCLIC ACRYLAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-09-14 | — | — | WO | disclosed |
| EP-0833630-A4 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN INC (US) | 1998-09-02 | — | — | EP | disclosed |
| CN-1187814-A | (hetero) aryloxy-, -thio-and-aminocrotonates, preparation and use thereof | BASF AG (DE) | 1998-07-15 | — | — | CN | disclosed |
| EP-0833630-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | Sugen, Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| CN-1161687-A | Phenylacetic acid alkyl esters | BASF AG (DE) | 1997-10-08 | — | — | CN | disclosed |
| WO-1996040110-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| CN-1075962-A | DIOXOLANE DERIVATIVES | CIBA GEIGY AG (CH) | 1993-09-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118286-A1 | Heterobicyclic Acrylamides | CCNB1, C3AR1, CCNA2 | LTA4H 1390/4885TSHR 982/4885MAOB 1732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.