Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 3/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.37 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155064 | 0.78 | TRAP1 (0.55) | HDAC1HDAC2HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL4160380 | 0.72 | HSP90AA1 (0.46) | NAMPTHSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL13117451 | 0.67 | PRMT5 (0.58) | HDAC1HDAC2HSP90B1TRAP1 | |
| SCHEMBL6033529 | 0.65 | HSP90AA1 (0.39) | HDAC1HDAC2HSP90AA1CAMKK2GSK3B | |
| SCHEMBL19813866 | 0.65 | CAMKK2 (0.36) | HDAC1HDAC2CAMKK2GSK3BPIK3CD | |
| SCHEMBL19304618 | 0.62 | HPGD (0.46) | NAMPTHSP90AA1HSP90AB1GAA | |
| SCHEMBL1938417 | 0.62 | KMO (0.62) | — | |
| SCHEMBL1938421 | 0.62 | KMO (0.60) | — | |
| SCHEMBL6202952 | 0.62 | GSK3B (0.40) | HDAC1HDAC2NAMPTP2RX7GSK3B | |
| SCHEMBL940865 | 0.61 | KMO (0.57) | CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | HDAC1 176/4885HDAC2 303/4885NAMPT 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.