Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4524677 | 0.79 | MIF (0.47) | TRPA1ALDH1A1MIFHPGDCCR3 | |
| SCHEMBL1653 | 0.78 | ALDH1A1 (0.55) | TRPA1ALDH1A1CYP3A4MIFHPGD | |
| Hydrogen Sulfide SCHEMBL5079696 | 0.75 | ALDH1A1 (0.52) | TRPA1ALDH1A1CYP3A4MIFHPGD | |
| SCHEMBL4520548 | 0.72 | TAAR1 (0.38) | ALDH1A1SIGMAR1 | |
| SCHEMBL2145 | 0.72 | ALDH1A1 (0.50) | TRPA1ALDH1A1CYP3A4MIFHPGD | |
| SCHEMBL10325242 | 0.71 | TRPA1 (0.48) | TRPA1ALDH1A1CYP3A4MIFHPGD | |
| SCHEMBL2027845 | 0.69 | GBA1 (0.71) | ALDH1A1GBA1SIGMAR1CCR3GRIN2B | |
| SCHEMBL674276 | 0.69 | GBA1 (0.71) | ALDH1A1GBA1SIGMAR1CCR3GRIN2B | |
| SCHEMBL4165641 | 0.68 | ALDH1A1 (0.38) | ALDH1A1MIFGBA1SIGMAR1CCR3 | |
| SCHEMBL2242592 | 0.68 | ALDH1A1 (0.41) | TRPA1ALDH1A1CYP3A4MIFHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | TRPA1 1836/4885ALDH1A1 2505/4885CYP3A4 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.