Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157358 | 1.00 | ALDH1A1 (0.38) | ALDH1A1KDM4EMTNR1AMTNR1BTP53 | |
| SCHEMBL4143069 | 0.95 | MTNR1A (0.37) | ALDH1A1KDM4EMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL4143066 | 0.95 | MTNR1A (0.37) | ALDH1A1KDM4EMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL4152580 | 0.94 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL4152577 | 0.94 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL4153074 | 0.92 | ESR1 (0.35) | ALDH1A1MTNR1AMTNR1BLMNAMAPT | |
| SCHEMBL4153077 | 0.92 | ESR1 (0.35) | ALDH1A1MTNR1AMTNR1BLMNAMAPT | |
| SCHEMBL4156042 | 0.92 | PRKCA (0.38) | ALDH1A1KDM4EMTNR1AMTNR1BTP53 | |
| SCHEMBL4156040 | 0.92 | PRKCA (0.38) | ALDH1A1KDM4EMTNR1AMTNR1BTP53 | |
| SCHEMBL4139777 | 0.92 | CPT2 (0.34) | CPT2CPT1AOPRM1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | IDO1, IDO2, ZC3HAV1 | ALDH1A1 754/4885KDM4E 2269/4885MTNR1A 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.