SCHEMBL415801

SCHEMBL415801

O=C(O)C(O)(c1ccccc1)C1CCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 1.00
NFE2L2 Q16236 1/20 1.00
CHRM3 P20309 12/20 0.59
CHRM2 P08172 6/20 0.59
CHRM1 P11229 5/20 0.59
ALDH1A1 P00352 2/20 0.55
CHRM4 P08173 1/20 0.52
CHRM5 P08912 1/20 0.52
HRH1 P35367 1/20 0.52
HTR2B P41595 1/20 0.52
KCNH2 Q12809 1/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2062949 1.00 KEAP1 (1.00) KEAP1NFE2L2CHRM3CHRM2CHRM1
SCHEMBL418664 1.00 KEAP1 (1.00) KEAP1NFE2L2CHRM3CHRM2CHRM1
Iodide SCHEMBL16713396 0.98 KEAP1 (0.96) KEAP1NFE2L2CHRM3CHRM2CHRM1
SCHEMBL2764243 0.98 KEAP1 (0.96) KEAP1NFE2L2CHRM3CHRM2CHRM1
SCHEMBL198312 0.98 KEAP1 (0.96) KEAP1NFE2L2CHRM3CHRM2CHRM1
SCHEMBL1235433 0.98 KEAP1 (0.96) KEAP1NFE2L2CHRM3CHRM2CHRM1
SCHEMBL198082 0.98 KEAP1 (0.96) KEAP1NFE2L2CHRM3CHRM2CHRM1
SCHEMBL3909615 0.98 KEAP1 (0.96) KEAP1NFE2L2CHRM3CHRM2CHRM1
Hydrochloric Acid SCHEMBL7269393 0.98 KEAP1 (0.96) KEAP1NFE2L2CHRM3CHRM2CHRM1
SCHEMBL29903954 0.98 KEAP1 (0.96) KEAP1NFE2L2CHRM3CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 699 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302975-A1 METHODS AND COMPOSITIONS FOR AGONISING TLR3 UNITED STATES GOVERNMENT 2025-10-02 US claimed
US-12358908-B2 Crystals, preparation method and application of a muscarinic receptor antagonist BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) 2025-07-15 US claimed
EP-3842419-B1 METHOD OF MAKING THREO GLYCOPYRROLATE TOSYLATE JOURNEY MEDICAL CORP (US) 2024-04-03 EP claimed
CN-113461585-B Synthesis process of glycopyrronium bromide 安徽普利药业有限公司 2023-10-31 CN claimed
CN-116208351-A Malicious node detection framework for resisting CPMA attack in Internet of things 南京航空航天大学 2023-06-02 CN claimed
US-20230167107-A1 CRYSTALS, PREPARATION METHOD AND APPLICATION OF A MUSCARINIC RECEPTOR ANTAGONIST BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) 2023-06-01 US claimed
CN-106769697-B Real-time tracking and measuring device and method for thermodynamic properties of atmospheric nanoparticles 北京大学 2023-05-16 CN claimed
EP-4144733-A1 CRYSTAL OF M RECEPTOR ANTAGONIST AS WELL AS PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Beijing Showby Pharmaceutical Co., Ltd. (CN) 2023-03-08 EP claimed
US-11542232-B2 Process for production of glycopyrronium tosylate JOURNEY MEDICAL CORPORATION (US) 2023-01-03 US claimed
CN-115397823-A M receptor antagonist crystal, preparation method and application thereof 北京硕佰医药科技有限责任公司 2022-11-25 CN claimed
CN-1673209-A Active metabolic product of phencynonate and its medicinal use INST OF TOXICANT PHARMACOLOGY (CN) 2005-09-28 CN claimed
US-20040072863-A1 Novel quinuclidine derivatives and medicinal compositions containing the same ALMIRALL, S.A. (ES) 2004-04-15 US claimed
EP-1353919-A2 NOVEL QUINUCLIDINE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME Almirall Prodesfarma AG (CH) 2003-10-22 EP claimed
EP-0734724-B1 PROCESS FOR THE PREPARATION OF A PHENCYNONATE HYDROCHLORIDE OF ALPHA-CONFIGURATION INST PHARM & TOXICOLOGY AMMS (CN) 2003-08-20 EP claimed
WO-2002053564-A2 QUINUCLIDINE DERIVATIVES AND THEIR USE AS M3 ANTAGONISTS ALMIRALL PRODESFARMA AG (CH) 2002-07-11 WO claimed
US-6028198-A CATALYTIC ESTERIFICATION OF 3-METHYL AZABICYCLO (3, 3, 1) NONAN-9 ALPHA-OL WITH METHYL OR ETHYL 2-PHENYL-2-CYCLOPENTYL-2-HYDROXY-ACETATE OR 2-PHENYL-2-CYCLOPENTYL-2-HYDROXY-ACETIC ACID INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY SCIENCES P.L.A. (CN) 2000-02-22 US claimed
CN-1045956-C Method for preparing benzene ring nonyl ester INST OF POISON & MEDICINE ACAD (CN) 1999-10-27 CN claimed
CN-1182738-A Method for preparing benzene ring nonyl ester INST OF POISON AND MEDICINE MI (CN) 1998-05-27 CN claimed
EP-0734724-A1 A COMPOSITION FOR PREVENTING AND TREATING KINETOTIA SYNDROME Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) 1996-10-02 EP claimed
CN-1089838-A Pharmaceutical composition for preventing and treating motion sickness syndrome INST OF POISON MATERIAL MEDICA (CN) 1994-07-27 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167107-A1 CRYSTALS, PREPARATION METHOD AND APPLICATION OF A MUSCARINIC RECEPTOR ANTAGONIST CHRM5, CHRM2, CHRM3 KEAP1 4502/4885NFE2L2 4008/4885CHRM3 3/4885
US-20040072863-A1 Novel quinuclidine derivatives and medicinal compositions containing the same CYP11B1, CYP3A7, CBR1 KEAP1 1020/4885NFE2L2 901/4885CHRM3 26/4885
US-12358908-B2 Crystals, preparation method and application of a muscarinic receptor antagonist CHRM5, CHRM2, CHRM3 KEAP1 4502/4885NFE2L2 4008/4885CHRM3 3/4885
US-11542232-B2 Process for production of glycopyrronium tosylate TPO, GYPA, THRA KEAP1 4660/4885NFE2L2 4800/4885CHRM3 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.