SCHEMBL415802

SCHEMBL415802

O=C(OC1CCCC1)[C@H](O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.64
CYP2D6 P10635 4/20 0.64
CYP2C9 P11712 2/20 0.64
HSD17B10 Q99714 2/20 0.64
CHRM2 P08172 4/20 0.62
CHRM1 P11229 4/20 0.62
CHRM3 P20309 4/20 0.62
CHRM4 P08173 3/20 0.62
CHRM5 P08912 3/20 0.62
BLM P54132 3/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
NR1I2 O75469 1/20 0.56
ABCB11 O95342 1/20 0.56
THRB P10828 2/20 0.51
PMP22 Q01453 2/20 0.51
MEN1 O00255 1/20 0.51
CYP1A2 P05177 1/20 0.51
MTOR P42345 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2062723 1.00 LMNA (0.64) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL3916189 1.00 LMNA (0.64) LMNACYP2D6CYP2C9HSD17B10CHRM2
Iodide SCHEMBL16713395 0.98 LMNA (0.62) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL7274518 0.98 LMNA (0.62) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL198313 0.98 LMNA (0.62) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL198083 0.98 LMNA (0.62) LMNACYP2D6CYP2C9HSD17B10CHRM2
Hydrochloric Acid SCHEMBL7269400 0.98 LMNA (0.62) LMNACYP2D6CYP2C9HSD17B10CHRM2
Hydrochloric Acid SCHEMBL7268076 0.97 LMNA (0.61) LMNACYP2D6CYP2C9HSD17B10CHRM2
Hydrochloric Acid SCHEMBL8987487 0.95 LMNA (0.59) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL17294713 0.85 LMNA (0.59) LMNACYP2D6CYP2C9HSD17B10CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358908-B2 Crystals, preparation method and application of a muscarinic receptor antagonist BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) 2025-07-15 US claimed
CN-119019241-B Synthesis method of alpha-cyclopentyl mandelic acid 深圳智微通科技有限公司 2025-02-07 CN claimed
CN-119019241-A Synthesis method of alpha-cyclopentyl mandelic acid 深圳智微通科技有限公司 2024-11-26 CN claimed
EP-3842419-B1 METHOD OF MAKING THREO GLYCOPYRROLATE TOSYLATE JOURNEY MEDICAL CORP (US) 2024-04-03 EP claimed
CN-113461585-B Synthesis process of glycopyrronium bromide 安徽普利药业有限公司 2023-10-31 CN claimed
US-20230167107-A1 CRYSTALS, PREPARATION METHOD AND APPLICATION OF A MUSCARINIC RECEPTOR ANTAGONIST BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) 2023-06-01 US claimed
EP-4144733-A1 CRYSTAL OF M RECEPTOR ANTAGONIST AS WELL AS PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Beijing Showby Pharmaceutical Co., Ltd. (CN) 2023-03-08 EP claimed
US-11542232-B2 Process for production of glycopyrronium tosylate JOURNEY MEDICAL CORPORATION (US) 2023-01-03 US claimed
CN-115397823-A M receptor antagonist crystal, preparation method and application thereof 北京硕佰医药科技有限责任公司 2022-11-25 CN claimed
CN-215538608-U Be used for alpha-cyclopentyl mandelic acid active carbon decoloration device 天津佶品佳化工科技有限公司 2022-01-18 CN claimed
US-20190225580-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE DERMIRA, INC. 2019-07-25 US claimed
US-10294201-B2 Process for production of glycopyrronium tosylate DERMIRA, INC. (US) 2019-05-21 US claimed
US-20180186735-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE SWK FUNDING LLC 2018-07-05 US claimed
US-9926270-B2 Process for production of glycopyrronium tosylate DERMIRA, INC. (US) 2018-03-27 US claimed
US-20160052879-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE SWK FUNDING LLC 2016-02-25 US claimed
EP-2961734-A1 GLYCOPYRROLATE SALTS Dermira, Inc. (US) 2016-01-06 EP claimed
WO-2014134510-A1 GLYCOPYRROLATE SALTS DERMIRA, INC. (US) 2014-09-04 WO claimed
EP-2485678-A1 COFERONS AND METHODS OF MAKING AND USING THEM Cornell University (US) 2012-08-15 EP claimed
WO-2011043817-A1 COFERONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2011-04-14 WO claimed
US-20090005577-A1 Method of producing 1-substituted 3-pyrrolates KRAIOUCHKINE NIKOLAI 2009-01-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005577-A1 Method of producing 1-substituted 3-pyrrolates GYPA, GIPR, PGA5 LMNA 4465/4885CYP2D6 486/4885CYP2C9 694/4885
US-20160052879-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE TPO, GYPA, THRA LMNA 4690/4885CYP2D6 610/4885CYP2C9 958/4885
US-20230167107-A1 CRYSTALS, PREPARATION METHOD AND APPLICATION OF A MUSCARINIC RECEPTOR ANTAGONIST CHRM5, CHRM2, CHRM3 LMNA 3370/4885CYP2D6 3292/4885CYP2C9 2069/4885
US-20180186735-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE TPO, GYPA, THRA LMNA 4690/4885CYP2D6 610/4885CYP2C9 958/4885
US-10294201-B2 Process for production of glycopyrronium tosylate TPO, GYPA, THRA LMNA 4690/4885CYP2D6 610/4885CYP2C9 958/4885
US-20190225580-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE TPO, GYPA, THRA LMNA 4690/4885CYP2D6 610/4885CYP2C9 958/4885
US-12358908-B2 Crystals, preparation method and application of a muscarinic receptor antagonist CHRM5, CHRM2, CHRM3 LMNA 3370/4885CYP2D6 3292/4885CYP2C9 2069/4885
US-11542232-B2 Process for production of glycopyrronium tosylate TPO, GYPA, THRA LMNA 4690/4885CYP2D6 610/4885CYP2C9 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.