Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233999 | 0.89 | POLB (0.54) | NPSR1ALDH1A1GAAMAPTMAPK8 | |
| SCHEMBL13041354 | 0.87 | NPSR1 (0.51) | NPSR1ALDH1A1GAAMAPTMAPK8 | |
| SCHEMBL11468077 | 0.84 | TP53 (0.62) | NPSR1ALDH1A1GAAMAPTMAPK8 | |
| SCHEMBL26474681 | 0.84 | ALDH1A1 (0.53) | NPSR1ALDH1A1GAAMAPTMAPK8 | |
| SCHEMBL13019308 | 0.82 | SMN1; SMN2 (0.54) | NPSR1ALDH1A1GAAMAPTMAPK8 | |
| SCHEMBL20014923 | 0.82 | MAPK1 (0.58) | NPSR1ALDH1A1GAAMAPTMAPK8 | |
| SCHEMBL2989345 | 0.81 | LMNA (0.51) | NPSR1ALDH1A1GAAMAPTMAPK8 | |
| SCHEMBL3740328 | 0.81 | PPARG (0.46) | NPSR1ALDH1A1GAAMAPTMAPK8 | |
| SCHEMBL2897094 | 0.81 | POLB (0.74) | NPSR1ALDH1A1GAAMAPTTSHR | |
| SCHEMBL1866493 | 0.81 | PPARG (0.46) | NPSR1ALDH1A1GAAMAPTMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176825-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2009-07-09 | — | — | US | disclosed |
| US-7553849-B2 | Compounds | ACTIVE BIOTECH AB (SE) | 2009-06-30 | — | — | US | disclosed |
| EP-1776369-B1 | THIENOPYRIDONE CARBOXAMIDES AND THEIR MEDICAL USE | ACTIVE BIOTECH AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| US-20060004038-A1 | Novel compounds | ACTIVE BIOTECH AB (SE) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004038-A1 | Novel compounds | REL, CLIC4, C5 | NPSR1 1423/4885ALDH1A1 3955/4885GAA 4880/4885 |
| US-20090176825-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | NPSR1 1973/4885ALDH1A1 319/4885GAA 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.