SCHEMBL4159192

SCHEMBL4159192

CC(C)C[C@H](N)C(=O)O[Si](OC(C)(C)C)(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.42
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
ANPEP P15144 2/20 0.33
RNPEP Q9H4A4 2/20 0.33
DNPEP Q9ULA0 1/20 0.33
AAK1 Q2M2I8 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4147433 0.83
SCHEMBL4160100 0.80 GRIN2D (0.33)
SCHEMBL4149894 0.77 ALOX15 (0.43)
SCHEMBL4162429 0.77 SLC7A5 (0.37) SLC7A5
SCHEMBL2541315 0.76 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL66234 0.76 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL66233 0.76 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL7318373 0.76 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL7318378 0.76 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL4153755 0.76 MARS1 (0.33) RNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090099307-A1 Inverse solid phase peptide synthesis with additional capping step ACTIVOTEC SPP LIMITED (GB) 2009-04-16 US disclosed
US-20080242836-A1 Convergent Solid Phase Peptide Synthesis By Reaction Of Two Fragments Bound To Solid Support UNIVERSITY OF SOUTHAMPTON (GB) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099307-A1 Inverse solid phase peptide synthesis with additional capping step RNGTT, CPSF7, CPSF1 SLC7A5 1663/4885SLC1A3 3264/4885SLC1A2 4168/4885
US-20080242836-A1 Convergent Solid Phase Peptide Synthesis By Reaction Of Two Fragments Bound To Solid Support CPSF1, CPSF7, MAX SLC7A5 1096/4885SLC1A3 1499/4885SLC1A2 2596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.