Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TOP2A | P11388 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162331 | 0.81 | RAB9A (0.43) | ALDH1A1TOP2AKDM4EGAAUSP2 | |
| SCHEMBL13696902 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAUSP2GLA | |
| SCHEMBL4149713 | 0.80 | KDM4E (0.51) | ALDH1A1KDM4EGAAGLACYP3A4 | |
| SCHEMBL13696992 | 0.79 | HSD17B10 (0.50) | ALDH1A1KDM4EGAAUSP2GLA | |
| SCHEMBL15624437 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4ETLR7GAAUSP2 | |
| SCHEMBL13696899 | 0.77 | HIF1A (0.49) | ALDH1A1TOP2AKDM4EGAAGLA | |
| SCHEMBL10007438 | 0.75 | TDP1 (0.77) | ALDH1A1KDM4EL3MBTL1CYP3A4MAPT | |
| SCHEMBL4163816 | 0.75 | PSMB8 (0.39) | ALDH1A1KDM4EGAAGLACYP3A4 | |
| SCHEMBL14540241 | 0.73 | TDP1 (0.63) | ALDH1A1L3MBTL1TDP1APP | |
| SCHEMBL10900609 | 0.73 | LMNA (0.58) | ALDH1A1GAAL3MBTL1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127164-B2 | Fluorescent dyes and uses thereof | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| EP-1940965-B1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ALMAC SCIENCES SCOTLAND LTD (GB) | 2014-03-26 | — | — | EP | disclosed |
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ACR, ANXA5, GLB1 | ALDH1A1 97/4885TOP2A 2875/4885KDM4E 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.