Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 18/20 | 0.62 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.62 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.62 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735578 | 0.84 | POLB (0.56) | HSP90AA1POLB | |
| SCHEMBL4151310 | 0.83 | HSP90AA1 (0.78) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL16735658 | 0.81 | POLB (0.53) | HSP90AA1HSP90AB1POLB | |
| SCHEMBL16735619 | 0.80 | POLB (0.52) | HSP90AA1POLB | |
| SCHEMBL16735643 | 0.79 | LMNA (0.53) | POLB | |
| SCHEMBL16735639 | 0.79 | RXFP1 (0.46) | HSP90AA1POLB | |
| SCHEMBL16735667 | 0.79 | POLB (0.51) | POLB | |
| SCHEMBL16735605 | 0.78 | POLB (0.51) | POLB | |
| SCHEMBL16735666 | 0.77 | LMNA (0.53) | POLB | |
| SCHEMBL16735593 | 0.77 | RXFP1 (0.56) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |