Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7047762 | 0.98 | MEN1 (0.48) | ALDH1A1MEN1KMT2ATDP1CHRM2 | |
| SCHEMBL11146572 | 0.91 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL16389231 | 0.90 | MEN1 (0.42) | ALDH1A1MEN1KMT2ATDP1CHRM2 | |
| SCHEMBL13926497 | 0.90 | CHRM2 (0.50) | ALDH1A1MEN1KMT2ATDP1CHRM2 | |
| SCHEMBL14275024 | 0.90 | MAOA (0.55) | ALDH1A1CHRM2MAOAHRH4HRH3 | |
| SCHEMBL7935225 | 0.89 | MC4R (0.45) | ALDH1A1MEN1KMT2ATDP1CHRM2 | |
| SCHEMBL28585721 | 0.88 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2ATDP1CHRM2 | |
| SCHEMBL15927522 | 0.88 | HRH4 (0.47) | ALDH1A1MEN1KMT2ATDP1CHRM2 | |
| SCHEMBL4017967 | 0.88 | MC4R (0.47) | ALDH1A1MEN1KMT2ATDP1CHRM2 | |
| Hydrochloric Acid SCHEMBL7123283 | 0.87 | MC4R (0.44) | ALDH1A1MEN1KMT2ATDP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150196586-A1 | POLYMERIC MOLECULAR RECEPTORS AS PHOSPHATE SEQUESTRANTS | GENZYME CORPORATION | 2015-07-16 | — | — | US | disclosed |
| US-20150196586-A1 | POLYMERIC MOLECULAR RECEPTORS AS PHOSPHATE SEQUESTRANTS | GENZYME CORPORATION | 2015-07-16 | — | — | US | disclosed |
| US-20150196586-A1 | POLYMERIC MOLECULAR RECEPTORS AS PHOSPHATE SEQUESTRANTS | GENZYME CORPORATION | 2015-07-16 | — | — | US | disclosed |
| US-8986669-B2 | Method for removing phosphate and polymer used therefore | GENZYME CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |
| US-8986669-B2 | Method for removing phosphate and polymer used therefore | GENZYME CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |
| US-8986669-B2 | Method for removing phosphate and polymer used therefore | GENZYME CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |
| US-20090162314-A1 | Magnesium-Containing Polymers for the Treatment of Hyperphosphatemia | GENZYME CORPORATION | 2009-06-25 | — | — | US | disclosed |
| US-20090047233-A1 | Method for removing Phosphate and Polymer Used Therefore | GENZYME CORPORATION | 2009-02-19 | — | — | US | disclosed |
| US-20090047233-A1 | Method for removing Phosphate and Polymer Used Therefore | GENZYME CORPORATION | 2009-02-19 | — | — | US | disclosed |
| US-20090047233-A1 | Method for removing Phosphate and Polymer Used Therefore | GENZYME CORPORATION | 2009-02-19 | — | — | US | disclosed |
| EP-1951266-A2 | METHOD FOR REMOVING PHOSPHATE AND POLYMER USED THEREFORE | Genzyme Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1945196-A2 | MAGNESIUM-CONTAINING POLYMERS FOR HYPERPHOSPHATEMIA | Genzyme Corporation (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056405-A2 | MAGNESIUM-CONTAINING POLYMERS FOR THE TREATMENT OF HYPERPHOSPHATEMIA | GENZYME CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007027566-A2 | METHOD FOR REMOVING PHOSPHATE AND POLYMER USED THEREFORE | GENZYME CORPORATION (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027566-A2 | METHOD FOR REMOVING PHOSPHATE AND POLYMER USED THEREFORE | GENZYME CORPORATION (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047233-A1 | Method for removing Phosphate and Polymer Used Therefore | PHPT1, PNKP, PHYKPL | ALDH1A1 4473/4885MEN1 1271/4885KMT2A 4501/4885 |
| US-20150196586-A1 | POLYMERIC MOLECULAR RECEPTORS AS PHOSPHATE SEQUESTRANTS | PHPT1, SLC34A2, SLC34A1 | ALDH1A1 4361/4885MEN1 2884/4885KMT2A 4429/4885 |
| US-20090162314-A1 | Magnesium-Containing Polymers for the Treatment of Hyperphosphatemia | PPIP5K2, PHPT1, PHOSPHO1 | ALDH1A1 4615/4885MEN1 13/4885KMT2A 2820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.