Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12308200 | 0.90 | HDAC1 (0.58) | POLBLMNANPC1RAB9AKMT2A | |
| SCHEMBL11220601 | 0.88 | LMNA (0.85) | POLBLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL8414232 | 0.85 | HDAC6 (0.53) | POLBLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8415068 | 0.85 | HDAC1 (0.51) | POLBLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL12308254 | 0.84 | HDAC3 (0.53) | POLBLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16144546 | 0.82 | LMNA (0.76) | POLBLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL9489979 | 0.82 | L3MBTL1 (0.86) | POLBLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL765958 | 0.82 | L3MBTL1 (0.74) | POLBLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL764574 | 0.82 | MMP13 (0.81) | POLBLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL8414393 | 0.82 | POLB (0.56) | POLBLMNAMMP13ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030099-A1 | FOAM COMPOSITION AND FOAM | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |