Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | UBE2M | P61081 | 2/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4164045 | 0.90 | TSHR (0.44) | SIGMAR1UBE2MDCUN1D1TSHR | |
| Trifluoroacetic Acid SCHEMBL4606072 | 0.90 | SIGMAR1 (0.52) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4171437 | 0.84 | SIGMAR1 (0.47) | SIGMAR1ACHEBCHE | |
| Trifluoroacetic Acid SCHEMBL4161039 | 0.84 | SIGMAR1 (0.57) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4154002 | 0.83 | CYP2C19 (0.48) | SIGMAR1UBE2MDCUN1D1TSHRKMT2A | |
| Trifluoroacetic Acid SCHEMBL4622701 | 0.82 | CHRM1 (0.46) | SIGMAR1UBE2MDCUN1D1 | |
| Trifluoroacetic Acid SCHEMBL4150100 | 0.78 | CHRM2 (0.42) | SIGMAR1UBE2MDCUN1D1TSHRKMT2A | |
| Trifluoroacetic Acid SCHEMBL4159827 | 0.77 | BCHE (0.42) | CCR2ACHEBCHEKMT2A | |
| SCHEMBL4164039 | 0.76 | HDAC1 (0.41) | KMT2A | |
| Trifluoroacetic Acid SCHEMBL4164232 | 0.72 | SIGMAR1 (0.43) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | CCR2 3695/4885SIGMAR1 3623/4885ACHE 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.