Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4161039 | 0.93 | SIGMAR1 (0.57) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4164045 | 0.91 | TSHR (0.44) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4159826 | 0.90 | CCR2 (0.49) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4154002 | 0.87 | CYP2C19 (0.48) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4622701 | 0.85 | CHRM1 (0.46) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4171437 | 0.85 | SIGMAR1 (0.47) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4150100 | 0.81 | CHRM2 (0.42) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL4304780 | 0.78 | CES1 (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL4164876 | 0.78 | BCHE (0.42) | — | |
| SCHEMBL4166891 | 0.76 | CES1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945609-A2 | AMINO ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007029036-A2 | AMINO ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |