Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218786 | 0.82 | GABRR1 (0.36) | GABRR1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL14439278 | 0.82 | GABRR1 (0.36) | GABRR1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL799755 | 0.82 | GABRR1 (0.36) | GABRR1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL21757620 | 0.82 | GABRR1 (0.36) | GABRR1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL20363529 | 0.77 | GABRR1 (0.33) | GABRR1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL17453292 | 0.74 | GABRR1 (0.32) | GABRR1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL29550605 | 0.71 | GABRR1 (0.42) | GABRR1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL13758787 | 0.67 | ALDH1A1 (0.35) | GABRR1LMNA | |
| SCHEMBL415680 | 0.67 | GABRR1 (0.34) | GABRR1MAPK1TSHRHSD17B10 | |
| SCHEMBL10020532 | 0.67 | ALDH1A1 (0.35) | GABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220056488-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA INC (US) | 2022-02-24 | — | — | US | disclosed |
| US-20200332320-A1 | MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS | GENOMATICA, INC. | 2020-10-22 | — | — | US | disclosed |
| US-10793882-B2 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | GENOMATICA, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-10385344-B2 | Microorganisms and methods for the biosynthesis of (2-hydroxy-3methyl-4-oxobutoxy) phosphonate | GENOMATICA, INC. (US) | 2019-08-20 | — | — | US | disclosed |
| US-20190032095-A1 | MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS | GENOMATICA, INC. | 2019-01-31 | — | — | US | disclosed |
| US-10059967-B2 | Microorganisms and processes for producing terephthalic acid and its salts | GENOMATICA, INC. (US) | 2018-08-28 | — | — | US | disclosed |
| EP-3312284-A2 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | Genomatica, Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| US-20170335352-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | AGAIN BIO APS (DK) | 2017-11-23 | — | — | US | disclosed |
| EP-2607340-B1 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | GENOMATICA INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9556461-B2 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | GENOMATICA, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150004662-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF (2-HYDROXY-3METHYL-4-OXOBUTOXY) PHOSPHONATE | GENOMATICA INC (US) | 2015-01-01 | — | — | US | disclosed |
| US-8715957-B2 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | GENOMATICA, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| WO-2013109865-A2 | MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS | GENOMATICA, INC. (US) | 2013-07-25 | — | — | WO | disclosed |
| EP-2607340-A1 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | Genomatica, Inc. (US) | 2013-06-26 | — | — | EP | disclosed |
| EP-2529011-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE | Genomatica, Inc. (US) | 2012-12-05 | — | — | EP | disclosed |
| WO-2012018624-A2 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| US-20120021478-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | AGAIN BIO APS (DK) | 2012-01-26 | — | — | US | disclosed |
| US-20110207185-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE | GENOMATICA, INC. | 2011-08-25 | — | — | US | disclosed |
| US-20110207185-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE | GENOMATICA, INC. | 2011-08-25 | — | — | US | disclosed |
| WO-2011094131-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE | GENOMATICA, INC. (US) | 2011-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190032095-A1 | MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS | HPD, PAH, TST | GABRR1 3297/4885CES2 1969/4885MAPK1 1200/4885 |
| US-10059967-B2 | Microorganisms and processes for producing terephthalic acid and its salts | HPD, PAH, TST | GABRR1 2943/4885CES2 2257/4885MAPK1 1006/4885 |
| US-20200332320-A1 | MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS | HPD, PAH, TST | GABRR1 3297/4885CES2 1969/4885MAPK1 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.