Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | CHAT | P28329 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160704 | 1.00 | KDM4E (0.47) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL4165008 | 0.83 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL2886094 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1MAPTCYP2D6HPGD | |
| SCHEMBL11808866 | 0.73 | MAPT (0.64) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11808860 | 0.73 | MAPT (0.64) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL4159068 | 0.71 | KDM4E (0.54) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL4155634 | 0.70 | L3MBTL1 (0.41) | KDM4EL3MBTL1MAPTSIGMAR1RAB9A | |
| SCHEMBL4155639 | 0.70 | L3MBTL1 (0.41) | KDM4EL3MBTL1MAPTSIGMAR1RAB9A | |
| SCHEMBL342910 | 0.69 | KDM4E (0.59) | KDM4EALDH1A1MAPTCYP2D6HPGD | |
| SCHEMBL14668870 | 0.69 | KDM4E (0.56) | KDM4EALDH1A1MAPTCYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212048-B2 | Method of producing aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| CN-101410375-B | Process for producing aromatic compound | SUMITOMO CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101410375-A | Process for producing aromatic compound | SUMITOMO CHEMICAL CO (JP) | 2009-04-15 | — | — | CN | disclosed |
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | AHR, CYP1A1, ARNT | KDM4E 3177/4885MEN1 1053/4885KMT2A 1770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.