Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GLA | P06280 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27961721 | 0.79 | MAPT (0.59) | KMT2AALDH1A1GLAKDM4EHPGD | |
| SCHEMBL29097354 | 0.79 | HTR3A (0.55) | HTR3AKMT2AALDH1A1GLAKDM4E | |
| SCHEMBL4160733 | 0.77 | ALDH1A1 (0.60) | HTR3AKMT2AALDH1A1GLAKDM4E | |
| SCHEMBL28335934 | 0.75 | MAPT (0.54) | KMT2AALDH1A1GLAKDM4EHPGD | |
| SCHEMBL11715187 | 0.72 | CYP2A6 (0.50) | ALDH1A1HPGDGAAMAPTCASP1 | |
| Proflavine SCHEMBL3864747 | 0.71 | HTR3A (1.00) | HTR3AKMT2AALDH1A1GLAKDM4E | |
| SCHEMBL29911350 | 0.71 | TLR8 (0.53) | HTR3AKMT2AALDH1A1GLAKDM4E | |
| SCHEMBL1229699 | 0.71 | HTR3A (1.00) | HTR3AKMT2AALDH1A1GLAKDM4E | |
| SCHEMBL3300463 | 0.71 | TLR8 (0.53) | HTR3AKMT2AALDH1A1GLAKDM4E | |
| SCHEMBL17141873 | 0.70 | ALDH1A1 (0.61) | HTR3AKMT2AALDH1A1GLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465721-A | FROM DIHYDRIC PHENOL WITH CARBON MONOXIDE AND HYDROGEN | MCALISTER ROY E | 1984-08-14 | — | — | US | disclosed |
| US-4414364-A | ENDCAPPING WITH A HALOHYDROCARBON OR A TRIALKYL SILICON HALIDE | MCALISTER ROY E | 1983-11-08 | — | — | US | disclosed |
| US-4350663-A | ENDCAPPING POLYCARBONATES WITH GASEOUS REACTANT TO PROVIDE STRESS CORROSION RESISTANCE | MCALISTER ROY E | 1982-09-21 | — | — | US | disclosed |
| WO-1982001554-A1 | POLYCARBONATES STABILIZED BY HALOHYDROCARBON,HALOCARBON OR SILANE GROUPS | MCALISTER ROY E | 1982-05-13 | — | — | WO | disclosed |
| EP-0027144-A4 | POLYCARBONATES STABILIZED BY HALOHYDROCARBON, HALOCARBON OR SILANE GROUPS. | MCALISTER ROY E | 1981-05-19 | — | — | EP | disclosed |
| EP-0027144-A1 | POLYCARBONATES STABILIZED BY HALOHYDROCARBON, HALOCARBON OR SILANE GROUPS | McALISTER, Roy Edward (US) | 1981-04-22 | — | — | EP | disclosed |
| US-4243779-A | FLUORESCENCE, PHOTOSTABILITY | MCALISTER ROY E | 1981-01-06 | — | — | US | disclosed |
| WO-1980002290-A1 | POLYCARBONATES STABILIZED BY HALOHYDROCARBON,HALOCARBON OR SILANE GROUPS | MCALISTER R | 1980-10-30 | — | — | WO | disclosed |