Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP8 | P22894 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248817 | 0.89 | DGAT1 (0.64) | KDRNAMPTNR2E3DGAT1MEN1 | |
| SCHEMBL14642393 | 0.82 | TP53 (0.72) | TP53RXFP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1251055 | 0.80 | DGAT1 (0.79) | KDRNR2E3DGAT1TP53RXFP1 | |
| SCHEMBL1251122 | 0.76 | ALDH1A1 (0.65) | KDRNR2E3TP53MEN1KMT2A | |
| SCHEMBL13679620 | 0.76 | LDLR (0.65) | KDRTP53RXFP1ALDH1A1LMNA | |
| SCHEMBL3182256 | 0.76 | CHEK2 (0.60) | DGAT1TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL14615285 | 0.75 | MAPT (0.73) | TP53RXFP1MEN1KMT2ALMNA | |
| SCHEMBL1250204 | 0.74 | DGAT1 (0.64) | KDRNR2E3DGAT1MEN1KMT2A | |
| SCHEMBL23657828 | 0.74 | ACP1 (0.60) | KDRNAMPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13679578 | 0.73 | MAPT (0.73) | KDRTP53RXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074089-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-07-01 | — | — | EP | claimed |
| WO-2008048991-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-04-24 | — | — | WO | claimed |