Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 9/20 | 0.38 |
| ▸ | AKT2 | P31751 | 9/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274493 | 0.57 | LTA4H (0.46) | — | |
| SCHEMBL8370228 | 0.57 | LTA4H (0.46) | — | |
| SCHEMBL9340608 | 0.54 | RARB (0.35) | — | |
| SCHEMBL9185158 | 0.53 | RAB9A (0.67) | AKT1AKT2NPC1RAB9A | |
| SCHEMBL1318629 | 0.53 | AKT1 (0.53) | AKT1AKT2USP7 | |
| SCHEMBL30218059 | 0.53 | AKT1 (0.51) | AKT1AKT2USP7NPC1RAB9A | |
| SCHEMBL12920734 | 0.52 | COMT (0.55) | AKT1AKT2USP7NPC1RAB9A | |
| SCHEMBL12920739 | 0.52 | ADORA3 (0.43) | AKT1AKT2USP7NPC1RAB9A | |
| SCHEMBL2504442 | 0.51 | PIK3CD (0.55) | AKT1AKT2 | |
| SCHEMBL10875975 | 0.51 | LTA4H (0.37) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893245-A4 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | UNIV PENNSYLVANIA (US) | 2009-06-24 | — | — | EP | disclosed |
| EP-1893245-A2 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | The Trustees of the University of Pennsylvania (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007002540-A2 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | KUNG HANK F (US) | 2007-01-04 | — | — | WO | disclosed |