Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38665314 | 0.87 | TYR (0.49) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL11656789 | 0.85 | ALOX5 (0.55) | TYRALOX5CYP3A4TSHRPTGS2 | |
| SCHEMBL5677194 | 0.83 | TYR (0.68) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL15313674 | 0.83 | PTGS2 (0.47) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL15313670 | 0.83 | PTGS2 (0.47) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL15313669 | 0.83 | PTGS2 (0.47) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL4316141 | 0.83 | ALOX5 (0.57) | TYRALOX5CYP3A4TSHRPTGS2 | |
| SCHEMBL5678235 | 0.81 | TYR (0.66) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL5680424 | 0.80 | TYR (0.66) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL28121887 | 0.79 | TYR (0.43) | TYRALOX5TP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090081134-A1 | Oral Care Compositions Comprising Tropolone Compounds and Essential Oils and Methods of Using The Same | PAN PAULINE | 2009-03-26 | — | — | US | disclosed |
| EP-1622593-A1 | CONFECTIONERY PRODUCTS FOR DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS TO THE THROAT | Warner-Lambert Company LLC (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1536759-A1 | ORAL CARE COMPOSITION COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS | Warner-Lambert Company LLC (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20050002993-A1 | Confectionery products for delivery of pharmaceutically active agents to the throat | MCNEIL-PPC, INC | 2005-01-06 | — | — | US | disclosed |
| WO-2004096184-A1 | CONFECTIONERY PRODUCTS FOR DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS TO THE THROAT | WARNER-LAMBERT COMPANY LLC (US) | 2004-11-11 | — | — | WO | disclosed |
| US-20040185010-A1 | Oral care compositions comprising tropolone compounds and essential oils and methods of using the same | MCNEIL-PPC, INC | 2004-09-23 | — | — | US | disclosed |
| WO-2004012692-A1 | ORAL CARE COMPOSITION COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-12 | — | — | WO | disclosed |
| US-6689342-B1 | DENTISTRY | WARNER-LAMBERT COMPANY | 2004-02-10 | — | — | US | disclosed |
| US-20040018154-A1 | ORAL CARE COMPOSITIONS COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS AND METHODS OF USING THE SAME | MCNEIL-PPC, INC | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090081134-A1 | Oral Care Compositions Comprising Tropolone Compounds and Essential Oils and Methods of Using The Same | TMSB10, PIGS, TPM3 | TYR 55/4885ALOX5 37/4885TP53 1675/4885 |
| US-20040185010-A1 | Oral care compositions comprising tropolone compounds and essential oils and methods of using the same | TMSB10, PIGS, TPM3 | TYR 55/4885ALOX5 37/4885TP53 1675/4885 |
| US-20040018154-A1 | ORAL CARE COMPOSITIONS COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS AND METHODS OF USING THE SAME | TMSB10, PIGS, TPM3 | TYR 55/4885ALOX5 37/4885TP53 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.