Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | EYA2 | O00167 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL16004809 | 1.00 | KDM4E (0.73) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL5485760 | 1.00 | KDM4E (0.73) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL21043562 | 0.97 | KDM4E (0.70) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL17747958 | 0.97 | KDM4E (0.70) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Pentetic Acid SCHEMBL136882 | 0.97 | KDM4E (0.77) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL2170101 | 0.97 | KDM4E (0.70) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL906 | 0.97 | KDM4E (0.76) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL44287 | 0.97 | KDM4E (0.76) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL3835316 | 0.97 | KDM4E (0.76) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL42427 | 0.97 | KDM4E (0.76) | KDM4EALOX15MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15787 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146355-A1 | \"Golden\" - Gold Nanomaterials | AG-NANO SYSTEM LLC (US) | 2026-05-28 | — | — | US | claimed |
| EP-4743067-A1 | PHARMACEUTICAL FORMULATIONS FOR INHALATION AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-05-20 | — | — | EP | claimed |
| EP-4734772-A1 | EXTRUSION-ENCAPSULATED CALCIUM SALTS AS OPACIFYING/WHITENING AGENTS | Capol Inc. (CA) | 2026-05-06 | — | — | EP | claimed |
| WO-2026090627-A1 | STABLE PITOLISANT LIQUID FORMULATIONS AND METHOD OF ITS USE | PATEL SANDIPKUMAR (US) | 2026-04-30 | — | — | WO | claimed |
| EP-4732829-A1 | GLP-1-FC-FGF21 DOUBLE-TARGET FUSION PROTEIN COMPOSITION, AND INJECTION AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2026-04-29 | — | — | EP | claimed |
| US-12611531-B2 | Coated microneedle with multilayer structure, method for preparing the same and microneedle patch comprising coated microneedle | Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences (CN) | 2026-04-28 | — | — | US | claimed |
| EP-3892114-B1 | EFFERVESCENT BEVERAGE HAVING IMPROVED TASTE QUALITIES OF SUGAR AND SWEETENER | SUNTORY HOLDINGS LTD (JP) | 2026-04-22 | — | — | EP | claimed |
| EP-4719070-A1 | METHOD OF PREPARING IMPROVED PASTA FILATA CHEESE AND SAID PASTA FILATA CHEESE | Arla Foods amba (DK) | 2026-04-08 | — | — | EP | claimed |
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| EP-4260844-B1 | OPHTHALMOLOGICAL COMPOSITIONS COMPRISING POLOXAMER | LIEGNER JEFFERY T (US) | 2026-03-18 | — | — | EP | claimed |
| US-4734222-A | Composition and method for cleaning soft and hard contact lenses | CIBA-GEIGY CORPORATION (US) | 1988-03-29 | — | — | US | claimed |
| CN-86106616-A | Dertergent for washing away pollutant from heavy metals | — | 1987-04-22 | — | — | CN | claimed |
| EP-0208519-A2 | Solubilized composition of hardly-soluble pharmaceutical product | Takeda Chemical Industries, Ltd. (JP) | 1987-01-14 | — | — | EP | claimed |
| EP-0184942-A2 | Improved pharmaceutical composition containing 13-CIS vitamin a acid as the active ingredient | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-06-18 | — | — | EP | claimed |
| EP-0154009-A1 | Use of a thiazide diuretic for the manufacture of a non-diuretic antihypertensive medicament | Euro-Celtique S.A. (LU) | 1985-09-11 | — | — | EP | claimed |
| EP-0028813-B1 | STABLE SOLUTIONS OF HYDROGENATED ERGOTALCALOIDS OR THEIR SALTS AND HEPARIN OR ITS SALTS,AND PROCESS FOR THEIR PREPARATIONS | SANDOZ AG (CH) | 1984-07-25 | — | — | EP | claimed |
| EP-0023161-B1 | PROCESS FOR THE MODIFICATION OF THE PHYSICAL AND BIOCHEMICAL CHARACTERISTICS OF ANIMAL BLOOD AFTER SLAUGHTERING, DEVICE FOR THE APPLICATION OF THE PROCESS, INDUSTRIAL PRODUCTS OBTAINED AND DERIVED APPLICATIONS | Balsse, Christian (FR) | 1983-07-13 | — | — | EP | claimed |
| US-4299853-A | Biological preservation of beer | Schoorlemmer, Ben | 1981-11-10 | — | — | US | claimed |
| US-4195084-A | Taste-stable aqueous pharmaceutical suspension of tall oil sitosterols and a method for the preparation thereof | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | claimed |
| US-4107331-A | Zinc chelating fungicidal composition | ROSENBERG MAX | 1978-08-15 | — | — | US | claimed |