Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.42 |
| ▸ | ACHE | P22303 | 8/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | NMT2 | O60551 | 6/20 | 0.40 |
| ▸ | NMT1 | P30419 | 6/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.39 |
| ▸ | CHRNG | P07510 | 2/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.39 |
| ▸ | CHRND | Q07001 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4606072 | 0.78 | SIGMAR1 (0.52) | — | |
| Trifluoroacetic Acid SCHEMBL4304780 | 0.76 | CES1 (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL4164879 | 0.75 | CES1 (0.37) | ACHE | |
| SCHEMBL4158065 | 0.75 | CES1 (0.45) | CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL4606734 | 0.74 | NPY1R (0.46) | — | |
| SCHEMBL4166891 | 0.74 | CES1 (0.52) | CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL4605724 | 0.73 | CES1 (0.46) | CHRNA1CHRNGCHRNB1CHRND | |
| Trifluoroacetic Acid SCHEMBL4620633 | 0.72 | CCR2 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL4164045 | 0.72 | TSHR (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL4161039 | 0.72 | SIGMAR1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | BCHE 777/4885ACHE 2183/4885CACNA1F 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.