SCHEMBL416515

SCHEMBL416515

CCCCCCCCCCC/C=C\CCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCC/C=C\CCCCCCCCCCC

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.88
NR5A2 O00482 1/20 0.88
NR5A1 Q13285 1/20 0.88
MAPT P10636 1/20 0.78
ALDH1A1 P00352 1/20 0.78
FABP3 P05413 1/20 0.70
RECQL P46063 1/20 0.69
ADRA1D P25100 1/20 0.59
PTAFR P25105 1/20 0.59
HTR1D P28221 1/20 0.59
HTR2C P28335 1/20 0.59
ADRA1B P35368 1/20 0.59
DRD3 P35462 1/20 0.59
TMEM97 Q5BJF2 1/20 0.59
PRKCE Q02156 1/20 0.58
PRKCQ Q04759 1/20 0.58
PRKCD Q05655 1/20 0.58
PRKCA P17252 1/20 0.58
SELP P16109 1/20 0.57
ENPP2 Q13822 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159882 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL15709161 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL178155 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL234634 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL23188433 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL235532 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL25354838 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL45162 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL22492184 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1
SCHEMBL1649042 1.00 SMN1; SMN2 (0.88) SMN1; SMN2NR5A2NR5A1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743094-A1 LIPOSOMAL FORMULATIONS OF CORTICOSTEROIDS AND USES THEREOF Eden Ophthalmic Pte Ltd. (SG) 2026-05-20 EP claimed
WO-2025015046-A1 LIPOSOMAL FORMULATIONS OF CORTICOSTEROIDS AND USES THEREOF EDEN OPHTHALMIC PTE LTD. (SG) 2025-01-16 WO claimed
EP-4482511-A2 COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS The Regents of The University of Michigan (US) 2025-01-01 EP claimed
WO-2023164476-A2 COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-08-31 WO claimed
US-20220354963-A1 EXTRACELLULAR VESICLE LINKED TO MOLECULES AND USES THEREOF CODIAK BIOSCIENCES, INC. (US) 2022-11-10 US claimed
EP-2444464-A1 Novel neutral (bio)material Centre National de la Recherche Scientifique (CNRS) (FR) 2012-04-25 EP claimed
US-20080118489-A1 Charge-Modified Lysozyme Antimicrobial Compositions, Surfactants, and Methods for Infections and Cystic Fibrosis THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2008-05-22 US claimed
EP-4731266-A1 NANOPARTICLE COMPOSITIONS ASSOCIATED WITH PEPTIDES The Regents of the University of Michigan (US) 2026-04-29 EP disclosed
EP-4637812-A1 HEPATITIS B COMPOSITIONS GlaxoSmithKline Biologicals S.A. (BE) 2025-10-29 EP disclosed
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 US disclosed
WO-2025133951-A1 IONIZABLE LIPIDS SUITABLE FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2025-06-26 WO disclosed
EP-4539876-A2 RECOMBINANT RNA MOLECULES COMPRISING UNTRANSLATED REGIONS OR SEGMENTS ENCODING SPIKE PROTEIN FROM THE OMICRON STRAIN OF SEVERE ACUTE RESPIRATORY CORONAVIRUS-2 GlaxoSmithKline Biologicals S.A. (BE) 2025-04-23 EP disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 EP disclosed
WO-2010053489-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2010-05-14 WO disclosed
EP-2081552-A2 SPONTANEOUSLY FORMING ELLIPSOIDAL PHOSPHOLIPID UNILAMELLAR VESICLES Children's Hospital Medical Center (US) 2009-07-29 EP disclosed
US-20090142267-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER 2009-06-04 US disclosed
EP-2020988-A2 COMPOSITIONS COMPRISING FUSOGENIC PROTEINS OR POLYPEPTIDES DERIVED FROM PROSAPOSIN FOR APPLICATION IN TRANSMEMBRANE DRUG DELIVERY SYSTEMS Children's Hospital Medical Center (US) 2009-02-11 EP disclosed
US-20080118489-A1 Charge-Modified Lysozyme Antimicrobial Compositions, Surfactants, and Methods for Infections and Cystic Fibrosis THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2008-05-22 US disclosed
WO-2008051818-A2 SPONTANEOUSLY FORMING ELLIPSOIDAL PHOSPHOLIPID UNILAMELLAR VESICLES CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2008-05-02 WO disclosed
WO-2007127439-A2 COMPOSITIONS COMPRISING FUSOGENIC PROTEINS OR POLYPEPTIDES DERIVED FROM PROSAPOSIN FOR APPLICATION IN TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2007-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR SMN1; SMN2 1150/4885NR5A2 2095/4885NR5A1 3094/4885
US-20220354963-A1 EXTRACELLULAR VESICLE LINKED TO MOLECULES AND USES THEREOF EXOSC5, EXOSC4, EXOSC10 SMN1; SMN2 1847/4885NR5A2 4354/4885NR5A1 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.