Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4606076 | 0.90 | KCNH2 (0.46) | KCNH2OPRM1SLC2A1SIGMAR1CES1 | |
| Trifluoroacetic Acid SCHEMBL4164046 | 0.89 | SLC2A1 (0.40) | KCNH2OPRM1SLC2A1SIGMAR1CES1 | |
| Trifluoroacetic Acid SCHEMBL4159827 | 0.87 | BCHE (0.42) | KCNH2SLC2A1CES1CHRM2CHRM3 | |
| Trifluoroacetic Acid SCHEMBL4161040 | 0.85 | SIGMAR1 (0.43) | KCNH2OPRM1SLC2A1SIGMAR1CES1 | |
| Trifluoroacetic Acid SCHEMBL4156617 | 0.85 | ACHE (0.41) | KCNH2SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL4154008 | 0.85 | CHRM2 (0.38) | KCNH2OPRM1SLC2A1SIGMAR1CES1 | |
| SCHEMBL4165142 | 0.82 | CES1 (0.37) | CES1 | |
| Trifluoroacetic Acid SCHEMBL4622705 | 0.82 | ALDH1A1 (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL4171441 | 0.81 | CHRM3 (0.42) | SIGMAR1CHRM2CHRM3 | |
| Trifluoroacetic Acid SCHEMBL4156616 | 0.72 | CHRM4 (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | KCNH2 3380/4885OPRM1 3936/4885SLC2A1 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.