Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4161823 | 0.87 | ABCB1 (0.67) | MEN1LMNATP53CYP3A4MAPT | |
| SCHEMBL4166843 | 0.85 | CYP1A1 (0.55) | CYP1A1CYP1A2L3MBTL1ABCB1ACHE | |
| SCHEMBL4157444 | 0.84 | CYP19A1 (0.63) | MEN1TP53CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL4408819 | 0.84 | CYP1A1 (0.49) | MEN1LMNATP53CYP3A4MAPT | |
| SCHEMBL4410884 | 0.82 | CYP1A1 (0.54) | CYP1A1CYP1A2L3MBTL1SIGMAR1 | |
| SCHEMBL7683484 | 0.82 | CYP1A1 (0.54) | CYP1A1CYP1A2L3MBTL1SIGMAR1 | |
| SCHEMBL7933562 | 0.82 | CYP3A4 (0.81) | MEN1LMNATP53CYP3A4MAPT | |
| SCHEMBL4407561 | 0.81 | CYP1A1 (0.48) | MEN1KMT2ACYP1A1CYP1A2L3MBTL1 | |
| SCHEMBL4152247 | 0.81 | SIGMAR1 (0.65) | CYP1A1CYP1A2SIGMAR1 | |
| SCHEMBL4150940 | 0.81 | ABCG2 (0.48) | MEN1TP53CYP3A4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
| US-20020147353-A1 | Novel flavonoids | VERENIGING CHRISTELIJK WETENSCHAPPELIJK ANDERWIJS (NL) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147353-A1 | Novel flavonoids | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, ABCC8 | MEN1 2151/4885LMNA 1184/4885TP53 730/4885 |
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | MEN1 4830/4885LMNA 2889/4885TP53 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.