Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | TP53 | P04637 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.69 |
| ▸ | TNKS | O95271 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27618931 | 0.89 | SMN1; SMN2 (0.76) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL27493025 | 0.89 | SMN1; SMN2 (1.00) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL30540840 | 0.89 | SMN1; SMN2 (1.00) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL31499219 | 0.85 | CYP3A4 (0.77) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL4160583 | 0.84 | TNKS (0.64) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL4172232 | 0.83 | MAPT (0.74) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| 7-Methoxyflavone SCHEMBL1373009 | 0.82 | TNKS (1.00) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL4166841 | 0.82 | MEN1 (0.55) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL28639665 | 0.80 | MAPT (0.82) | CYP3A4SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL27609731 | 0.80 | ABCB1 (0.69) | CYP3A4SMN1; SMN2TP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245922-B1 | PREPARED BY REACTING AN ELECTROPHILIC 2-ALKENYL AZALACTONE WITH A NUCLEOPHILIC AROMATIC KETONE; CAN BE COPOLYMERIZED WITH ACRYLIC MONOMERS AND PHOTOACTIVATED BY ACTINIC RADIATION TO CROSSLINK THE POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2001-06-12 | — | — | US | disclosed |
| EP-0837844-B1 | ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND | MINNESOTA MINING & MFG (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0837844-A1 | ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997005101-A1 | ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-02-13 | — | — | WO | disclosed |