Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4166937 | 0.82 | FABP4 (0.36) | ALDH1A1GAACES1MEN1KMT2A | |
| SCHEMBL4169539 | 0.77 | MAPT (0.41) | ALDH1A1GAA | |
| SCHEMBL4605614 | 0.77 | CES1 (0.45) | ALDH1A1GAACES1MEN1KMT2A | |
| SCHEMBL4156708 | 0.77 | CCKBR (0.34) | CES1MEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL4606348 | 0.76 | POLB (0.39) | CES1MEN1KMT2AFABP4HDAC1 | |
| SCHEMBL4164039 | 0.75 | HDAC1 (0.41) | ALDH1A1GAACES1MEN1KMT2A | |
| SCHEMBL3507605 | 0.74 | GPR139 (0.42) | GAAMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL4159631 | 0.74 | HDAC4 (0.47) | ALDH1A1MEN1KMT2AHDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL4156514 | 0.74 | SMN1; SMN2 (0.37) | MEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL4154125 | 0.73 | PADI4 (0.41) | ALDH1A1GAAMEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | ALDH1A1 320/4885GAA 503/4885CES1 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.