Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3644747 | 0.85 | HSD11B1 (0.43) | HSD11B1HSD11B2ALDH1A1L3MBTL1HTT | |
| SCHEMBL20952430 | 0.81 | ALDH1A1 (0.47) | HSD11B1ALDH1A1L3MBTL1HTTPKM | |
| SCHEMBL25891422 | 0.78 | HSD11B1 (0.41) | HSD11B1ALDH1A1L3MBTL1HTTNPSR1 | |
| SCHEMBL25574064 | 0.77 | HSD11B1 (0.36) | HSD11B1HSD11B2 | |
| SCHEMBL7974713 | 0.76 | HSD11B1 (0.39) | HSD11B1ALDH1A1L3MBTL1HTTNPSR1 | |
| SCHEMBL24133558 | 0.75 | ALDH1A1 (0.36) | HSD11B1HSD11B2ALDH1A1HTTNPSR1 | |
| SCHEMBL1033879 | 0.75 | HSD11B1 (0.40) | HSD11B1HSD11B2ALDH1A1L3MBTL1HTT | |
| SCHEMBL24133999 | 0.75 | HSD11B1 (0.40) | HSD11B1HSD11B2ALDH1A1L3MBTL1HTT | |
| SCHEMBL31178076 | 0.75 | GRM2 (0.31) | NPSR1 | |
| SCHEMBL12517622 | 0.74 | HSD11B1 (0.38) | HSD11B1HSD11B2ALDH1A1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149504-A1 | Novel 5-Substituted Indole Derivatives As Dipeptidyl Peptidase IV (DPP-IV) Inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149504-A1 | Novel 5-Substituted Indole Derivatives As Dipeptidyl Peptidase IV (DPP-IV) Inhibitors | DPP4, DPP3, DPP7 | HSD11B1 674/4885HSD11B2 901/4885ALDH1A1 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.