SCHEMBL1033879

SCHEMBL1033879

O=C(O)C12CC3CC(C1)C(O)C(C3)C2

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 8/20 0.40
HSD11B2 P80365 5/20 0.40
CYP2C9 P11712 1/20 0.39
DGAT1 O75907 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
PKM P14618 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HTT P42858 1/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24133999 1.00 HSD11B1 (0.40) HSD11B1HSD11B2CYP2C9DGAT1L3MBTL1
SCHEMBL3644747 0.89 HSD11B1 (0.43) HSD11B1HSD11B2DGAT1L3MBTL1PKM
SCHEMBL28776246 0.84 CYP2C9 (0.40) HSD11B1CYP2C9L3MBTL1KDM4EHTT
SCHEMBL19557168 0.81 HSD11B1 (0.48) HSD11B1CYP2C9L3MBTL1PKMKDM4E
SCHEMBL19557166 0.81 HSD11B1 (0.48) HSD11B1CYP2C9L3MBTL1PKMKDM4E
SCHEMBL12714 0.81 HSD11B1 (0.48) HSD11B1CYP2C9L3MBTL1PKMKDM4E
SCHEMBL1844825 0.81 HSD11B1 (0.40) HSD11B1HSD11B2CYP2C9DGAT1L3MBTL1
SCHEMBL22131023 0.81 HSD11B1 (0.43) HSD11B1HSD11B2DGAT1L3MBTL1PKM
SCHEMBL974023 0.81 HSD11B1 (0.40) HSD11B1HSD11B2CYP2C9DGAT1L3MBTL1
SCHEMBL24134002 0.81 HSD11B1 (0.39) HSD11B1HSD11B2CYP2C9L3MBTL1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11640114-B2 Compound, resin, photoresist composition and process for producing photoresist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-02 US disclosed
CN-107556244-B Fused ring compound, pharmaceutical composition and application thereof 上海迪诺医药科技有限公司 2021-09-03 CN disclosed
US-20210255545-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-08-19 US disclosed
US-20200326625-A1 COMPOUND, RESIN, PHOTORESIST COMPOSITION AND PROCESS FOR PRODUCING PHOTORESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-10-15 US disclosed
CN-107438611-B fused ring compound, pharmaceutical composition and application thereof SHANGHAI DE NOVO PHARMATECH CO.,LTD. (CN) 2019-10-29 CN disclosed
WO-2019184919-A1 ADAMANTANE-CONTAINING COMPOUND AND USE THEREOF IN TREATING CANCER 成都海创药业有限公司 2019-10-03 WO disclosed
US-20190107778-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-11 US disclosed
US-10202388-B2 Fused-ring compounds, pharmaceutical composition and uses thereof Shanghai De Novo Pharmatech Co., Ltd. (CN) 2019-02-12 US disclosed
US-20180022752-A1 FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF Shanghai De Novo Pharmatech Co., Ltd. (CN) 2018-01-25 US disclosed
US-20180022752-A1 FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF Shanghai De Novo Pharmatech Co., Ltd. (CN) 2018-01-25 US disclosed
EP-0732333-B1 Indazolecarboxamides LILLY CO ELI (US) 2001-08-01 EP disclosed
US-5817676-A 5-HT4 RECEPTOR ANTAGONISTS, CARDIOVASCULAR DISORDERS ELI LILLY AND COMPANY (US) 1998-10-06 US disclosed
US-5798367-A ANTAGONIZE 5-HYDROXYTRYPTAMINE RECEPTOR IN GASTROINTESTINAL TRACT OR GENITOURINARY TRACT ELI LILLY AND COMPANY (US) 1998-08-25 US disclosed
EP-0619316-B1 Xanthine derivatives KYOWA HAKKO KOGYO KK (JP) 1998-08-12 EP disclosed
CN-1183041-A Indazolecarboxamides LILLY CO ELI (US) 1998-05-27 CN disclosed
US-5654320-A SEROTONIN RECEPTOR ANTAGONIST ELI LILLY AND COMPANY (US) 1997-08-05 US disclosed
WO-1996033713-A1 INDAZOLECARBOXAMIDES ELI LILLY AND COMPANY (US) 1996-10-31 WO disclosed
EP-0732333-A1 Indazolecarboxamides ELI LILLY AND COMPANY (US) 1996-09-18 EP disclosed
US-5395836-A Adenosine A1 receptor antagonists KYOWA HAKKO KOGYO CO., LTD. (JP) 1995-03-07 US disclosed
EP-0619316-A1 Xanthine derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1994-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200326625-A1 COMPOUND, RESIN, PHOTORESIST COMPOSITION AND PROCESS FOR PRODUCING PHOTORESIST PATTERN HAX1, BRIX1, RXRA HSD11B1 3373/4885HSD11B2 3734/4885CYP2C9 1426/4885
US-10202388-B2 Fused-ring compounds, pharmaceutical composition and uses thereof IDO1, IDO2, TDO2 HSD11B1 196/4885HSD11B2 127/4885CYP2C9 49/4885
US-20180022752-A1 FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF IDO1, IDO2, TDO2 HSD11B1 196/4885HSD11B2 127/4885CYP2C9 49/4885
US-20210255545-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN FGFR1, RER1, FGF1 HSD11B1 88/4885HSD11B2 140/4885CYP2C9 1168/4885
US-11640114-B2 Compound, resin, photoresist composition and process for producing photoresist pattern HAX1, BRIX1, RXRA HSD11B1 3373/4885HSD11B2 3734/4885CYP2C9 1426/4885
US-20190107778-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME CRY1, REN, SLC6A19 HSD11B1 97/4885HSD11B2 205/4885CYP2C9 1507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.