SCHEMBL4169754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1733478	0.86	BRD4 (0.49)	BRD4KEAP1KIF11KDM4EALDH1A1
	SCHEMBL13802151	0.78	BRD4 (0.44)	BRD4KEAP1KIF11KDM4EALDH1A1
	SCHEMBL17331932	0.77	BRD4 (0.43)	BRD4KEAP1KIF11KDM4EALDH1A1
	SCHEMBL31560951	0.77	BRD4 (0.43)	BRD4KEAP1KIF11KDM4EALDH1A1
	SCHEMBL25353014	0.77	BRD4 (0.43)	BRD4KEAP1KIF11KDM4EALDH1A1
	SCHEMBL3932021	0.77	KEAP1 (0.41)	KEAP1KIF11KDM4EALDH1A1LMNA
	SCHEMBL25997028	0.77	PIK3CB (0.42)	KEAP1KIF11KDM4EALDH1A1LMNA
	SCHEMBL24355264	0.77	KIF11 (0.51)	BRD4KEAP1KIF11MAPT
	SCHEMBL16658367	0.74	EPHX2 (0.47)	BRD4KEAP1KIF11
	SCHEMBL16868358	0.74	HPGD (0.43)	BRD4KEAP1KIF11KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.