Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | HAAO | P46952 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30122985 | 0.83 | CLCN2 (0.40) | TAS2R14NOTUMRXRARXRBCES2 | |
| SCHEMBL9949591 | 0.81 | TDP1 (0.39) | TAS2R14NOTUMCES2KDM4EALDH1A1 | |
| SCHEMBL10053348 | 0.78 | TAS2R14 (0.51) | TAS2R14NOTUMRXRARXRBCES2 | |
| SCHEMBL27466963 | 0.75 | TAS2R14 (0.45) | TAS2R14NOTUMRXRARXRBCES2 | |
| SCHEMBL30634615 | 0.75 | TAS2R14 (0.45) | TAS2R14NOTUMRXRARXRBCES2 | |
| SCHEMBL1634606 | 0.75 | TAS2R14 (0.45) | TAS2R14NOTUMRXRARXRBCES2 | |
| SCHEMBL10053356 | 0.75 | — | — | |
| SCHEMBL9949885 | 0.75 | AR (0.31) | — | |
| SCHEMBL10053358 | 0.74 | NR3C1 (0.31) | — | |
| SCHEMBL29489588 | 0.74 | NPC1 (0.41) | TSHRSORT1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658841-B1 | PROCESS FOR PREPARING 3-ALKYLSULFINYLBENZOYL DERIVATIVES | BAYER IP GMBH (DE) | 2017-09-20 | — | — | EP | disclosed |
| CN-103534234-B | The preparation method of 3-alkylsulfinylbenzoyl derivant | 拜耳知识产权有限责任公司 | 2016-09-14 | — | — | CN | disclosed |
| EP-2595954-B1 | (4-TRIFLUORMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER IP GMBH (DE) | 2016-05-04 | — | — | EP | disclosed |
| CN-103119020-B | (4-trifluoromethyl-3-thiobenzoyl) cyclohexanedione and the purposes as weedicide thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-12 | — | — | CN | disclosed |
| CN-103534234-A | Process for preparing 3-alkylsulfinylbenzoyl derivatives | BAYER IP GMBH | 2014-01-22 | — | — | CN | disclosed |
| EP-2658841-A1 | PROCESS FOR PREPARING 3-ALKYLSULFINYLBENZOYL DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-11-06 | — | — | EP | disclosed |
| US-8563779-B2 | (4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| US-8455657-B2 | Process for the preparation of 3-alkylsulfinylbenzoyl derivatives | BAYER CROPSCIENCE AG (DE) | 2013-06-04 | — | — | US | disclosed |
| EP-2595954-A1 | (4-TRIFLUORMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| CN-103119020-A | (4-trifluormethyl-3-thiobenzoyl) cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG | 2013-05-22 | — | — | CN | disclosed |
| WO-2012089644-A1 | PROCESS FOR PREPARING 3-ALKYLSULFINYLBENZOYL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-07-05 | — | — | WO | disclosed |
| US-20120165540-A1 | PROCESS FOR THE PREPARATION OF 3-ALKYLSULFINYLBENZOYL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| WO-2012010574-A1 | (4-TRIFLUORMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165540-A1 | PROCESS FOR THE PREPARATION OF 3-ALKYLSULFINYLBENZOYL DERIVATIVES | CBR3, CBR1, CYP1B1 | TAS2R14 1961/4885NOTUM 2324/4885RXRA 1505/4885 |
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | CBR3, DDT, CYP4X1 | TAS2R14 1358/4885NOTUM 1045/4885RXRA 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.