SCHEMBL29489588

SCHEMBL29489588

Cc1nonc1NC(=O)c1ccc(C(F)(F)F)c([S+](C)[O-])c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.41
RAB9A P51151 6/20 0.40
RXFP1 Q9HBX9 1/20 0.40
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.36
CYP1A2 P05177 2/20 0.35
LMNA P02545 1/20 0.34
SORT1 Q99523 1/20 0.33
GPR65 Q8IYL9 1/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
STAT3 P40763 1/20 0.33
STAT1 P42224 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16739373 1.00 NPC1 (0.41) NPC1RAB9ARXFP1KMT2APOLB
SCHEMBL22126541 0.83 SORT1 (0.33) NPC1RAB9ACYP1A2LMNASORT1
SCHEMBL17409841 0.80 NPC1 (0.42) NPC1RAB9ARXFP1KMT2APOLB
SCHEMBL16293630 0.79 NPC1 (0.41) NPC1RAB9ARXFP1KMT2APOLB
SCHEMBL19977985 0.78 KDM4E (0.40) NPC1RAB9AKMT2ALMNAMEN1
SCHEMBL30614217 0.77 CSNK2A2 (0.34) NPC1RAB9ACYP1A2LMNASORT1
SCHEMBL29913855 0.77 CSNK2A2 (0.34) NPC1RAB9ACYP1A2LMNASORT1
SCHEMBL29115244 0.77 CSNK2A2 (0.34) NPC1RAB9ACYP1A2LMNASORT1
SCHEMBL16915424 0.77 NPC1 (0.42) NPC1RAB9ARXFP1KMT2APOLB
SCHEMBL19283622 0.76 ADCY8 (0.37) NPC1RAB9AKMT2ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504550-A Pyrrolidone herbicide 河南蓝创作物科学有限公司 2025-02-25 CN claimed
EP-4096400-A1 LIQUID SULFONYLUREA COMPOSITIONS FMC Agricultural Caribe Industries Ltd. (BM) 2022-12-07 EP claimed
EP-4683908-A1 SUBSTITUTED OXAZOLIDINONES AND IMIDAZOLINONES AS HERBICIDES FMC Corporation (US) 2026-01-28 EP disclosed
WO-2025111184-A1 SUBSTITUTED TETRAHYDROQUINOLINE AND TETRAHYDROQUINOXALINE HERBICIDES FMC CORPORATION (US) 2025-05-30 WO disclosed
EP-4554941-A1 HERBICIDAL BENZOXAZINES FMC Corporation (US) 2025-05-21 EP disclosed
WO-2025096734-A1 MICROCAPSULES FMC CORPORATION (US) 2025-05-08 WO disclosed
CN-111574510-B Pyrimidine as herbicide Oxyphenyl derivatives FMC 公司 2025-03-07 CN disclosed
CN-119546601-A Herbicidal benzoxazines FMC公司 2025-02-28 CN disclosed
WO-2025006659-A1 MIXTURES OF BIXLOZONE WITH PHOTOSYSTEM I ELECTRON DIVERTERS FMC CORPORATION (US) 2025-01-02 WO disclosed
CN-119039233-A Pyridazinone herbicides and pyridazinone intermediates for preparing the same FMC公司 2024-11-29 CN disclosed
CN-118994028-A Pyridazinone herbicides and pyridazinone intermediates for preparing the same FMC公司 2024-11-22 CN disclosed
US-20220361502-A9 STABILIZED LOW-CONCENTRATION METSULFURON-METHYL LIQUID COMPOSITION FMC CORP (US) 2022-11-17 US disclosed
WO-2022177892-A1 HERBICIDAL CYCLIC AMIDES N-SUBSTITUTED WITH A HALOALKYLSULFONYLANILIDE GROUP FMC CORPORATION (US) 2022-08-25 WO disclosed
EP-4033900-A1 ANTHRANILAMIDE COMPOSITION FMC CORPORATION (US) 2022-08-03 EP disclosed
WO-2022140309-A1 SUBSTITUTED PYRIDAZINONE HERBICIDES FMC CORPORTION (US) 2022-06-30 WO disclosed
CN-108137512-B Cyclic N-amide compounds useful as herbicides FMC公司 2022-05-31 CN disclosed
CN-110740646-B Herbicidal mixtures, compositions and methods FMC公司 2022-05-10 CN disclosed
CN-105764337-B Stable low concentration metsulfuron-methyl liquid composition FMC公司 2022-05-10 CN disclosed
CN-114430657-A Anthranilamide compositions FMC公司 2022-05-03 CN disclosed
EP-3976599-A1 PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES FMC CORPORATION (US) 2022-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220361502-A9 STABILIZED LOW-CONCENTRATION METSULFURON-METHYL LIQUID COMPOSITION FABP4, FADS2, LIPC NPC1 4202/4885RAB9A 3768/4885RXFP1 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.