Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14649899 | 0.84 | KDM4E (0.33) | KDM4ECYP19A1OPRM1OPRD1OPRK1 | |
| SCHEMBL13925835 | 0.84 | KDM4E (0.33) | KDM4ECYP19A1OPRM1OPRD1OPRK1 | |
| SCHEMBL12936738 | 0.84 | KDM4E (0.33) | KDM4ECYP19A1OPRM1OPRD1OPRK1 | |
| SCHEMBL2611791 | 0.82 | OPRM1 (0.33) | KDM4ECYP19A1OPRM1OPRD1OPRK1 | |
| SCHEMBL7080628 | 0.81 | USP2 (0.37) | KDM4ECYP19A1OPRM1OPRD1OPRK1 | |
| SCHEMBL28668092 | 0.81 | ALDH1A1 (0.32) | KDM4ECYP19A1OPRM1OPRD1OPRK1 | |
| SCHEMBL17791736 | 0.79 | CYP2C19 (0.31) | — | |
| SCHEMBL28810184 | 0.78 | NAAA (0.36) | KDM4E | |
| SCHEMBL17791738 | 0.78 | CYP2C19 (0.34) | — | |
| SCHEMBL17791675 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247608-B2 | Aminoacid derivatives containing a disulfanyl group in the form of mixed disulfanyl and aminopeptidase N inhibitors | PHARMALEADS (FR) | 2012-08-21 | — | — | US | disclosed |
| US-20090131509-A1 | Aminoacid Derivatives Containing a Disulfanyl Group in the form of Mixed Disulfanyl and Aminopeptidase N Inhibitors | PHARMALEADS (FR) | 2009-05-21 | — | — | US | disclosed |
| US-20090012153-A1 | AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS | PHARMALEADS (FR) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131509-A1 | Aminoacid Derivatives Containing a Disulfanyl Group in the form of Mixed Disulfanyl and Aminopeptidase N Inhibitors | HRH4, OPRL1, CNR2 | KDM4E 1353/4885CYP19A1 1085/4885OPRM1 5/4885 |
| US-20090012153-A1 | AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS | HRH4, CNR2, OPRM1 | KDM4E 1311/4885CYP19A1 1001/4885OPRM1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.