Potassium

Potassium

SCHEMBL4171863

CC1=Nc2c(ccc3c(S(=O)(=O)O)cccc23)C1(C)C.[K]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.42
CYP1A2 P05177 3/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
AURKA O14965 1/20 0.35
AURKB Q96GD4 1/20 0.35
ATIC P31939 2/20 0.34
SUMO2 P61956 1/20 0.34
SUMO1 P63165 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP2 Q9HC62 1/20 0.34
MPL P40238 6/20 0.33
NSD2 O96028 1/20 0.33
POLB P06746 1/20 0.33
IDE P14735 1/20 0.33
DUSP3 P51452 1/20 0.33
CCR6 P51684 1/20 0.33
BLM P54132 1/20 0.33
SNCA P37840 1/20 0.32
COMT P21964 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4885961 0.99 TTR (0.43) TTRCYP1A2MEN1KMT2AAURKA
SCHEMBL4255042 0.83 MPL (0.40) CYP1A2MEN1KMT2AATICSUMO2
SCHEMBL101082 0.83 MYC (0.36) TTRCYP1A2MEN1KMT2AAURKA
SCHEMBL633391 0.80 MPL (0.33) CYP1A2SUMO2SUMO1SENP7SENP2
SCHEMBL14566372 0.79 MEN1 (0.55) TTRCYP1A2MEN1KMT2AAURKA
SCHEMBL4437128 0.75 ALDH1A1 (0.35) CYP1A2MEN1KMT2ASUMO2SUMO1
SCHEMBL14958133 0.71 MEN1 (0.52) TTRCYP1A2MEN1KMT2AATIC
SCHEMBL30233642 0.70 TTR (0.75) TTRCYP1A2MEN1KMT2AAURKA
SCHEMBL29363198 0.70 TTR (0.75) TTRCYP1A2MEN1KMT2AAURKA
SCHEMBL6242 0.70 TTR (0.75) TTRCYP1A2MEN1KMT2AAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10442930-B2 Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels VISEN MEDICAL, INC. (US) 2019-10-15 US disclosed
US-20170283617-A1 Biocompatible N, N-Disubstituted Sulfonamide-Containing Fluorescent Dye Labels VISEN MEDICAL, INC. 2017-10-05 US disclosed
US-9574085-B2 Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels VISEN MEDICAL, INC. (US) 2017-02-21 US disclosed
EP-1934211-B1 BIOCOMPATIBLE N, N-DISUBSTITUTED SULFONAMIDE-CONTAINING FLUORESCENT DYE LABELS VISEN MEDICAL INC (US) 2017-01-11 EP disclosed
US-20090130024-A1 Biocompatible N, N-Disubstituted Sulfonamide-Containing Fluorescent Dye Labels VISEN MEDICAL, INC. 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170283617-A1 Biocompatible N, N-Disubstituted Sulfonamide-Containing Fluorescent Dye Labels DNPEP, FUT5, NES TTR 757/4885CYP1A2 4526/4885MEN1 1657/4885
US-20090130024-A1 Biocompatible N, N-Disubstituted Sulfonamide-Containing Fluorescent Dye Labels DNPEP, FUT5, NES TTR 757/4885CYP1A2 4526/4885MEN1 1657/4885
US-10442930-B2 Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels DNPEP, FUT5, NES TTR 757/4885CYP1A2 4526/4885MEN1 1657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.