Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 12/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.39 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.39 |
| ▸ | CTRC | Q99895 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ATIC | P31939 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437128 | 0.85 | ALDH1A1 (0.35) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL4885961 | 0.84 | TTR (0.43) | MPLSENP2SUMO2SUMO1SENP7 | |
| Potassium SCHEMBL4171863 | 0.83 | TTR (0.42) | MPLSENP2SUMO2SUMO1SENP7 | |
| SCHEMBL633391 | 0.80 | MPL (0.33) | MPLSENP2SUMO2SUMO1SENP7 | |
| SCHEMBL7701818 | 0.77 | MEN1 (0.54) | MPLSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL14958133 | 0.76 | MEN1 (0.52) | MPLSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL101082 | 0.76 | MYC (0.36) | MEN1KMT2ACYP1A2 | |
| SCHEMBL137432 | 0.75 | RXRA (0.30) | — | |
| SCHEMBL28705484 | 0.71 | NCOA3 (0.38) | MEN1KMT2ANSD2ALDH1A1CYP1A2 | |
| SCHEMBL23961228 | 0.70 | RXRA (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071388-B2 | Compositions and methods for biodetection by nucleic acid-templated chemistry | ENSEMBLE THERAPEUTICS CORPORATION (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071388-B2 | Compositions and methods for biodetection by nucleic acid-templated chemistry | ENSEMBLE THERAPEUTICS CORPORATION (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090275142-A1 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | ENSEMBLE THERAPEUTICS CORPORATION | 2009-11-05 | — | — | US | disclosed |
| US-20090275142-A1 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | ENSEMBLE THERAPEUTICS CORPORATION | 2009-11-05 | — | — | US | disclosed |
| EP-2066813-A2 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | Ensemble Discovery Corporation (US) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008054600-A2 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | ENSEMBLE DISCOVERY CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008054600-A2 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | ENSEMBLE DISCOVERY CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275142-A1 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | POLRMT, NT5C3B, RNGTT | MPL 4029/4885SENP2 3572/4885SENP1 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.