SCHEMBL4180629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4180631	1.00	APP (0.55)	APPRAF1ALOX5PTGS1PTGS2
	SCHEMBL8801250	1.00	APP (0.55)	APPRAF1ALOX5PTGS1PTGS2
	SCHEMBL698579	0.83	APP (0.72)	APPPTGS1PTGS2NFE2L2RELA
	SCHEMBL698580	0.83	APP (0.72)	APPPTGS1PTGS2NFE2L2RELA
	SCHEMBL4180021	0.81	APP (0.51)	APPALOX5PTGS1PTGS2NFE2L2
	SCHEMBL4171925	0.81	APP (0.51)	APPALOX5PTGS1PTGS2NFE2L2
	SCHEMBL4171932	0.81	APP (0.51)	APPALOX5PTGS1PTGS2NFE2L2
	SCHEMBL15177970	0.78	APP (0.67)	APPALOX5PTGS1PTGS2NFE2L2
	SCHEMBL699967	0.77	APP (0.70)	APPNFE2L2CYP1A1CYP1A2CYP1B1
	SCHEMBL12500811	0.77	NFE2L2 (0.56)	RAF1ALOX5PTGS1PTGS2NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.