SCHEMBL4172041

SCHEMBL4172041

C[C@@H]1CCCCC1NC(=O)c1c(F)c(F)cc(F)c1F

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 18/20 0.62
TAS1R1 Q7RTX1 17/20 0.62
TAS1R2 Q8TE23 17/20 0.62
MLYCD O95822 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4165729 1.00 TAS1R3 (0.62) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL4159246 1.00 TAS1R3 (0.62) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL4309782 0.87 TAS1R3 (0.66) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL4162795 0.87 TAS1R3 (0.66) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL4159220 0.87 TAS1R3 (0.66) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL702098 0.83 TAS1R3 (0.78) TAS1R3TAS1R1TAS1R2
SCHEMBL2453198 0.77 TAS1R3 (0.81) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL703197 0.77 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2
SCHEMBL701892 0.77 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL5270815 0.76 TAS1R3 (0.81) TAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers TAS2R10, TAS2R50, TAS2R8 TAS1R3 27/4885TAS1R1 23/4885TAS1R2 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.