SCHEMBL4159220

SCHEMBL4159220

CC1CCCCC1NC(=O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 17/20 0.66
TAS1R2 Q8TE23 16/20 0.66
TAS1R1 Q7RTX1 15/20 0.66
MLYCD O95822 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4162795 1.00 TAS1R3 (0.66) TAS1R3TAS1R2TAS1R1MLYCD
SCHEMBL4309782 1.00 TAS1R3 (0.66) TAS1R3TAS1R2TAS1R1MLYCD
SCHEMBL702098 0.92 TAS1R3 (0.78) TAS1R3TAS1R2TAS1R1
SCHEMBL4159246 0.87 TAS1R3 (0.62) TAS1R3TAS1R2TAS1R1MLYCD
SCHEMBL4172041 0.87 TAS1R3 (0.62) TAS1R3TAS1R2TAS1R1MLYCD
SCHEMBL4165729 0.87 TAS1R3 (0.62) TAS1R3TAS1R2TAS1R1MLYCD
SCHEMBL4177762 0.81 TAS1R3 (0.67) TAS1R3TAS1R2TAS1R1MLYCD
SCHEMBL4175575 0.81 TAS1R3 (0.59) TAS1R3TAS1R2TAS1R1
SCHEMBL701897 0.80 TAS1R3 (1.00) TAS1R3TAS1R2TAS1R1
SCHEMBL3101233 0.79 TAS1R3 (0.50) TAS1R3TAS1R2TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010756-A Preparation method, atomization liquid and atomization device of N- (2-methylcyclohexyl) -2,3,4,5, 6-pentafluorobenzamide 爱奇迹创造有限公司 2026-05-12 CN claimed
CN-119555829-A Detection method of N- (2-methylcyclohexyl) -2,3,4,5, 6-pentafluoro-benzamide and application thereof 东莞市鸿馥生物科技有限公司 2025-03-04 CN claimed
CN-116332790-A Process for preparing N- (2-methylcyclohexyl) -2,3,4,5,6-pentafluoro-benzamide by catalytic method and application thereof 昆山亚香香料股份有限公司 2023-06-27 CN claimed
CN-112423600-A Taste modifier composition, beverage and flavouring composition thereof 阿尔门德拉私人有限公司 2021-02-26 CN claimed
EP-3780970-A1 TASTE MODULATOR COMPOSITION, BEVERAGE AND FLAVORING COMPOSITION THEREOF Almendra Pte. Ltd. (SG) 2021-02-24 EP claimed
WO-2019202402-A1 TASTE MODULATOR COMPOSITION, BEVERAGE AND FLAVORING COMPOSITION THEREOF ALMENDRA PTE. LTD. (SG) 2019-10-24 WO claimed
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US claimed
CN-122010756-A Preparation method, atomization liquid and atomization device of N- (2-methylcyclohexyl) -2,3,4,5, 6-pentafluorobenzamide 爱奇迹创造有限公司 2026-05-12 CN disclosed
CN-122010756-A Preparation method, atomization liquid and atomization device of N- (2-methylcyclohexyl) -2,3,4,5, 6-pentafluorobenzamide 爱奇迹创造有限公司 2026-05-12 CN disclosed
CN-122010756-A Preparation method, atomization liquid and atomization device of N- (2-methylcyclohexyl) -2,3,4,5, 6-pentafluorobenzamide 爱奇迹创造有限公司 2026-05-12 CN disclosed
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS CORN PRODUCTS DEV INC (US) 2026-02-05 US disclosed
EP-4561366-A1 FLAVOR MODIFYING COMPOSITION CORN Products Development Inc. (US) 2025-06-04 EP disclosed
CN-119894387-A Flavor modulating composition 玉米产品开发公司 2025-04-25 CN disclosed
WO-2017075257-A2 HIGH INTENSITY SWEETENERS SENOMYX, INC. (US) 2017-05-04 WO disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 US disclosed
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS TAS2R42, TAS2R7, TAS2R31 TAS1R3 13/4885TAS1R2 10/4885TAS1R1 22/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 TAS1R3 9/4885TAS1R2 15/4885TAS1R1 2/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D TAS1R3 237/4885TAS1R2 284/4885TAS1R1 131/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 TAS1R3 102/4885TAS1R2 75/4885TAS1R1 126/4885
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers TAS2R10, TAS2R50, TAS2R8 TAS1R3 27/4885TAS1R2 11/4885TAS1R1 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.