Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MAN2A1 | Q16706 | 2/20 | 0.34 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014477 | 0.74 | SOS1 (0.50) | SOS1GRIN2BSIGMAR1GRIN1ALDH1A1 | |
| SCHEMBL3643057 | 0.71 | SOS1 (0.77) | SOS1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1808557 | 0.69 | SOS1 (0.82) | SOS1GRIN2BSIGMAR1GRIN1ALDH1A1 | |
| SCHEMBL10574503 | 0.66 | SOS1 (0.42) | SOS1ALDH1A1 | |
| SCHEMBL2087751 | 0.63 | SOS1 (0.51) | SOS1GRIN2BGRIN1HRH1 | |
| SCHEMBL25006478 | 0.63 | GRIN2B (0.78) | GRIN2BSIGMAR1GRIN1 | |
| SCHEMBL13952024 | 0.63 | SOS1 (0.59) | SOS1SIGMAR1ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL25006485 | 0.62 | GRIN2B (0.76) | GRIN2BSIGMAR1GRIN1 | |
| SCHEMBL3639265 | 0.62 | SOS1 (0.67) | SOS1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27099588 | 0.62 | HTR2C (0.49) | SIGMAR1ALDH1A1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143456-A1 | Polyamine Analogs as Modulators of Cell Migration and Cell Motility | PROGEN PHARMACEUTICALS, INC. | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143456-A1 | Polyamine Analogs as Modulators of Cell Migration and Cell Motility | SRM, MIF, PTGIS | SOS1 2530/4885GRIN2B 936/4885SIGMAR1 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.